Results 11 to 20 of about 74,807 (316)

Prostaglandins - universal biological regulators in the human body (literature review)

open access: yesZaporožskij Medicinskij Žurnal, 2018
Recently, researchers of different industries pay great attention to the problem of prostaglandins. Objective: to study and systematize the basic questions of structure, biological action and metabolism of prostaglandins in the human body and using ...
О. V. Tymoshchuk   +2 more
doaj   +2 more sources

Prostaglandin E Synthase, a Terminal Enzyme for Prostaglandin E2 Biosynthesis [PDF]

open access: yesBMB Reports, 2005
Biosynthesis of prostanoids is regulated by three sequential enzymatic steps, namely phospholipase A2 enzymes, cyclooxygenase (COX) enzymes, and various lineagespecific terminal prostanoid synthases. Prostaglandin E synthase (PGES), which isomerizes COX-derived PGH2 specifically to PGE2, occurs in multiple forms with distinct enzymatic properties ...
Ichiro, Kudo, Makoto, Murakami
openaire   +2 more sources

Prostaglandin synthesis in rat adrenocortical cells.

open access: yesJournal of Lipid Research, 1979
The biosynthesis of prostaglandins by isolated rat adrenocortical cells has been studied by determinations of products formed during incubations with labeled arachidonic acid and by radioimmunoassays.
R Chanderbhan   +3 more
doaj   +1 more source

Contribution of PGE2 EP1 receptor in hemin-induced neurotoxicity

open access: yesFrontiers in Molecular Neuroscience, 2013
Although hemin-mediated neurotoxicity has been linked to the production of free radicals and glutamate excitotoxicity, the role of the prostaglandin E2 (PGE2)-EP1 receptor remains unclear.
Shekher eMohan   +4 more
doaj   +1 more source

Hypothyroidism Affects Uterine Function via the Modulation of Prostaglandin Signaling

open access: yesAnimals, 2021
Thyroid hormones control the functions of almost all body systems. Reproductive dysfunctions, such as abnormal sexual development, infertility, or irregularities in the reproductive cycle, might be associated with thyroid disorders.
Ilona Kowalczyk-Zieba   +5 more
doaj   +1 more source

Dehydration of prostaglandins: study by spectroscopic method

open access: yesJournal of Lipid Research, 1969
The ultraviolet (UV) and optical rotatory dispersion (ORD) spectra of prostaglandins E1, A1, B1, and their naturally derived 15-epimers are presented.
Niels H. Andersen
doaj   +1 more source

Insights into the prostanoid pathway in the ovary development of the penaeid shrimp Penaeus monodon. [PDF]

open access: yesPLoS ONE, 2013
The prostanoid pathway converts polyunsaturated fatty acids (PUFAs) into bioactive lipid mediators, including prostaglandins, thromboxanes and prostacyclins, all of which play vital roles in the immune and reproductive systems in most animal phyla.
Wananit Wimuttisuk   +6 more
doaj   +1 more source

Docosahexaenoic acid-rich algae oil supplementation in mothers of preterm infants is associated with a modification in breast milk oxylipins profile

open access: yesLipids in Health and Disease, 2023
Oxylipins are derived from enzymatic and non-enzymatic oxidation of n-3 and n-6 long-chain polyunsaturated fatty acids. They are known to be involved in inflammatory processes.
Hélène Fougère   +7 more
doaj   +1 more source

Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion

open access: yesPharmacology Research & Perspectives, 2021
Chronic elevations in fatty acid metabolites termed prostaglandins can be found in circulation and in pancreatic islets from mice or humans with diabetes and have been suggested as contributing to the β‐cell dysfunction of the disease.
Harpreet K. Sandhu   +10 more
doaj   +1 more source

Gastroprotective activity of (E)-ethyl-12-cyclohexyl-4,5-dihydroxydodec-2-enoate, a compound isolated from Heliotropium indicum: role of nitric oxide, prostaglandins, and sulfhydryls in its mechanism of action

open access: yesPharmaceutical Biology, 2022
Context The gastroprotective effect of Heliotropium indicum L. (Boraginaceae), a plant traditionally used in Mexico to treat gastric ulcers, has been previously reported. However, no active compound was identified.Objective The current contribution aimed
Yaraset López-Lorenzo   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy