Results 11 to 20 of about 32,037,930 (259)

Contribution of PGE2 EP1 receptor in hemin-induced neurotoxicity

Frontiers in Molecular Neuroscience, 2013
Although hemin-mediated neurotoxicity has been linked to the production of free radicals and glutamate excitotoxicity, the role of the prostaglandin E2 (PGE2)-EP1 receptor remains unclear.
Shekher eMohan, Alexander V. Glushakov, Alexander edeCurnou, Shuh eNarumiya, Sylvain eDoré   +4 more
doaj   +1 more source

Hypothyroidism Affects Uterine Function via the Modulation of Prostaglandin Signaling

Animals, 2021
Thyroid hormones control the functions of almost all body systems. Reproductive dysfunctions, such as abnormal sexual development, infertility, or irregularities in the reproductive cycle, might be associated with thyroid disorders.
Ilona Kowalczyk-Zieba, Joanna Staszkiewicz-Chodor, Dorota Boruszewska, Krzysztof Lukaszuk, Joanna Jaworska, Izabela Woclawek-Potocka   +5 more
doaj   +1 more source

Dehydration of prostaglandins: study by spectroscopic method

Journal of Lipid Research, 1969
The ultraviolet (UV) and optical rotatory dispersion (ORD) spectra of prostaglandins E1, A1, B1, and their naturally derived 15-epimers are presented.
Niels H. Andersen
doaj   +1 more source

Insights into the prostanoid pathway in the ovary development of the penaeid shrimp Penaeus monodon. [PDF]

PLoS ONE, 2013
The prostanoid pathway converts polyunsaturated fatty acids (PUFAs) into bioactive lipid mediators, including prostaglandins, thromboxanes and prostacyclins, all of which play vital roles in the immune and reproductive systems in most animal phyla.
Wananit Wimuttisuk, Punsa Tobwor, Pacharawan Deenarn, Kannawat Danwisetkanjana, Decha Pinkaew, Kanyawim Kirtikara, Vanicha Vichai   +6 more
doaj   +1 more source

Prostaglandins - universal biological regulators in the human body (literature review)

Zaporožskij Medicinskij Žurnal, 2018
Recently, researchers of different industries pay great attention to the problem of prostaglandins. Objective: to study and systematize the basic questions of structure, biological action and metabolism of prostaglandins in the human body and using ...
О. V. Tymoshchuk, І. S. Lembryk, Z. R. Кocherga   +2 more
doaj   +1 more source

Docosahexaenoic acid-rich algae oil supplementation in mothers of preterm infants is associated with a modification in breast milk oxylipins profile

Lipids in Health and Disease, 2023
Oxylipins are derived from enzymatic and non-enzymatic oxidation of n-3 and n-6 long-chain polyunsaturated fatty acids. They are known to be involved in inflammatory processes.
Hélène Fougère, Karine Greffard, Mireille Guillot, Iwona Rudkowska, Etienne Pronovost, David Simonyan, Isabelle Marc, Jean-François Bilodeau   +7 more
doaj   +1 more source

Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion

Pharmacology Research & Perspectives, 2021
Chronic elevations in fatty acid metabolites termed prostaglandins can be found in circulation and in pancreatic islets from mice or humans with diabetes and have been suggested as contributing to the β‐cell dysfunction of the disease.
Harpreet K. Sandhu, Joshua C. Neuman, Michael D. Schaid, Sarah E. Davis, Kelsey M. Connors, Romith Challa, Erin Guthery, Rachel J. Fenske, Chinmai Patibandla, Richard M. Breyer, Michelle E. Kimple   +10 more
doaj   +1 more source

Gastroprotective activity of (E)-ethyl-12-cyclohexyl-4,5-dihydroxydodec-2-enoate, a compound isolated from Heliotropium indicum: role of nitric oxide, prostaglandins, and sulfhydryls in its mechanism of action

Pharmaceutical Biology, 2022
Context The gastroprotective effect of Heliotropium indicum L. (Boraginaceae), a plant traditionally used in Mexico to treat gastric ulcers, has been previously reported. However, no active compound was identified.Objective The current contribution aimed
Yaraset López-Lorenzo, María Elena Sánchez-Mendoza, Daniel Arrieta-Baez, Adriana Guadalupe Perez-Ruiz, Jesús Arrieta   +4 more
doaj   +1 more source

Bromoenol Lactone, an Inhibitor of Calcium-Independent Phospholipase A2, Suppresses Carrageenan-Induced Prostaglandin Production and Hyperalgesia in Rat Hind Paw

Mediators of Inflammation, 2015
Prostaglandin (PG) E2 and PGI2 are essential to hyperalgesia in inflammatory tissues. These prostaglandins are produced from arachidonic acid, which is cleaved from membrane phospholipids by the action of phospholipase A2 (PLA2). Which isozyme of PLA2 is
Keiichiro Tsuchida, Takae Ibuki, Kiyoshi Matsumura   +2 more
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Prostaglandins and related factors: XIX. Thin-layer chromatography of prostaglandins

Journal of Lipid Research, 1964
Methods are described for separation of all known prostaglandins and some derivatives as free acids and methyl esters by thin-layer chromatography both on analytical and preparative scales. The use of silica gel containing silver nitrate was required for
Krister Gréen, Bengt Samuelsson
doaj   +1 more source