Results 21 to 30 of about 141,844 (309)

Prostaglandins - universal biological regulators in the human body (literature review)

Zaporožskij Medicinskij Žurnal, 2018
Recently, researchers of different industries pay great attention to the problem of prostaglandins. Objective: to study and systematize the basic questions of structure, biological action and metabolism of prostaglandins in the human body and using ...
О. V. Tymoshchuk, І. S. Lembryk, Z. R. Кocherga   +2 more
doaj   +1 more source

Docosahexaenoic acid-rich algae oil supplementation in mothers of preterm infants is associated with a modification in breast milk oxylipins profile

Lipids in Health and Disease, 2023
Oxylipins are derived from enzymatic and non-enzymatic oxidation of n-3 and n-6 long-chain polyunsaturated fatty acids. They are known to be involved in inflammatory processes.
Hélène Fougère, Karine Greffard, Mireille Guillot, Iwona Rudkowska, Etienne Pronovost, David Simonyan, Isabelle Marc, Jean-François Bilodeau   +7 more
doaj   +1 more source

Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion

Pharmacology Research & Perspectives, 2021
Chronic elevations in fatty acid metabolites termed prostaglandins can be found in circulation and in pancreatic islets from mice or humans with diabetes and have been suggested as contributing to the β‐cell dysfunction of the disease.
Harpreet K. Sandhu, Joshua C. Neuman, Michael D. Schaid, Sarah E. Davis, Kelsey M. Connors, Romith Challa, Erin Guthery, Rachel J. Fenske, Chinmai Patibandla, Richard M. Breyer, Michelle E. Kimple   +10 more
doaj   +1 more source

Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue [PDF]

, 2020
Statin-related muscle side effects are a constant healthcare problem since patient compliance is dependent on side effects. Statins reduce plasma cholesterol levels and can prevent secondary cardiovascular diseases.
Dittmar, Gunnar, Grieben, Ulrike, Grunwald, Stefanie Anke, Haafke, Stefanie, Jedraszczak, Nicole, Kress, Wolfram, Patone, Giannino, Popp, Oliver, Saar, Kathrin, Spuler, Simone, Steinhagen-Thiessen, Elisabeth   +10 more
core   +1 more source

Gastroprotective activity of (E)-ethyl-12-cyclohexyl-4,5-dihydroxydodec-2-enoate, a compound isolated from Heliotropium indicum: role of nitric oxide, prostaglandins, and sulfhydryls in its mechanism of action

Pharmaceutical Biology, 2022
Context The gastroprotective effect of Heliotropium indicum L. (Boraginaceae), a plant traditionally used in Mexico to treat gastric ulcers, has been previously reported. However, no active compound was identified.Objective The current contribution aimed
Yaraset López-Lorenzo, María Elena Sánchez-Mendoza, Daniel Arrieta-Baez, Adriana Guadalupe Perez-Ruiz, Jesús Arrieta   +4 more
doaj   +1 more source

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]

, 2016
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio, Daugherty, Daniel, M Armando, Aaron, Maher, Pam, Quehenberger, Oswald, Schubert, David   +5 more
core   +2 more sources

Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes [PDF]

, 2015
Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition.
Aardema, Alves, Arsic, Asselin, Carluccio, Catov, Challis, Chen, Cheng, Cheng, Cheng, Cheng, Cherny, Chu, Crane, D.C. Wathes, D.R.E. Abayasekara, Flynn, Goncalves, Guillou, Herath, Jabbour, Karsch, Kim, Klein, Lamont, Lee, Leung, Lewis, Lunn, M. Elmes, Nielsen, Noble, Poyser, Reddy, Rimoldi, Robinson, S. Kirkup, Sharp, Smith, Smith, Thorburn, Villa, Wang, Wathes, Wendell, Whittle, Witkin, Z. Cheng, Zhang   +49 more
core   +2 more sources

Perfil inflamatorio del humor acuoso tras tratamiento asistido por láser de femtosegundo en casos de catarata nuclear

Revista Mexicana de Oftalmología, 2023
Objective: Femtosecond laser-assisted cataract surgery (FLACS) is a treatment with increasing popularity. However, inflammation generated by the laser remains a subject of research.
Claudia Palacio-Pastrana, Andric C. Perez-Ortiz, Bani Antonio-Aguirre, Cristina Mendoza-Velásquez, Azyadeh Camacho-Ordóñez, Manuel Ceballos-Reyes, Atzin Robles-Contreras, Virgilio Lima-Gómez   +7 more
doaj   +1 more source

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P, Hammock, Bruce D, Hennebelle, Marie, Kitson, Alex P, Lee, Kin Sing Stephen, Metherel, Adam H, Otoki, Yurika, Richardson, Christine E, Taha, Ameer Y, Yang, Jun, Zhang, Liang, Zhang, Zhichao   +11 more
core   +1 more source

Bromoenol Lactone, an Inhibitor of Calcium-Independent Phospholipase A2, Suppresses Carrageenan-Induced Prostaglandin Production and Hyperalgesia in Rat Hind Paw

Mediators of Inflammation, 2015
Prostaglandin (PG) E2 and PGI2 are essential to hyperalgesia in inflammatory tissues. These prostaglandins are produced from arachidonic acid, which is cleaved from membrane phospholipids by the action of phospholipase A2 (PLA2). Which isozyme of PLA2 is
Keiichiro Tsuchida, Takae Ibuki, Kiyoshi Matsumura   +2 more
doaj   +1 more source