Results 21 to 30 of about 31,003,476 (304)

Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion

open access: yesPharmacology Research & Perspectives, 2021
Chronic elevations in fatty acid metabolites termed prostaglandins can be found in circulation and in pancreatic islets from mice or humans with diabetes and have been suggested as contributing to the β‐cell dysfunction of the disease.
Harpreet K. Sandhu   +10 more
doaj   +1 more source

Gastroprotective activity of (E)-ethyl-12-cyclohexyl-4,5-dihydroxydodec-2-enoate, a compound isolated from Heliotropium indicum: role of nitric oxide, prostaglandins, and sulfhydryls in its mechanism of action

open access: yesPharmaceutical Biology, 2022
Context The gastroprotective effect of Heliotropium indicum L. (Boraginaceae), a plant traditionally used in Mexico to treat gastric ulcers, has been previously reported. However, no active compound was identified.Objective The current contribution aimed
Yaraset López-Lorenzo   +4 more
doaj   +1 more source

Bromoenol Lactone, an Inhibitor of Calcium-Independent Phospholipase A2, Suppresses Carrageenan-Induced Prostaglandin Production and Hyperalgesia in Rat Hind Paw

open access: yesMediators of Inflammation, 2015
Prostaglandin (PG) E2 and PGI2 are essential to hyperalgesia in inflammatory tissues. These prostaglandins are produced from arachidonic acid, which is cleaved from membrane phospholipids by the action of phospholipase A2 (PLA2). Which isozyme of PLA2 is
Keiichiro Tsuchida   +2 more
doaj   +1 more source

Prostaglandins and related factors: XIX. Thin-layer chromatography of prostaglandins

open access: yesJournal of Lipid Research, 1964
Methods are described for separation of all known prostaglandins and some derivatives as free acids and methyl esters by thin-layer chromatography both on analytical and preparative scales. The use of silica gel containing silver nitrate was required for
Krister Gréen, Bengt Samuelsson
doaj   +1 more source

Biochemical warfare on the reef: the role of glutathione transferases in consumer tolerance of dietary prostaglandins. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Despite the profound variation among marine consumers in tolerance for allelochemically-rich foods, few studies have examined the biochemical adaptations underlying diet choice. Here we examine the role of glutathione S-transferases (GSTs) in
Kristen E Whalen   +3 more
doaj   +1 more source

Perfil inflamatorio del humor acuoso tras tratamiento asistido por láser de femtosegundo en casos de catarata nuclear

open access: yesRevista Mexicana de Oftalmología, 2023
Objective: Femtosecond laser-assisted cataract surgery (FLACS) is a treatment with increasing popularity. However, inflammation generated by the laser remains a subject of research.
Claudia Palacio-Pastrana   +7 more
doaj   +1 more source

Choline Glycerophospholipid-Derived Prostaglandins Attenuate TNFα Gene Expression in Macrophages via a cPLA2α/COX-1 Pathway

open access: yesCells, 2021
Macrophages are professional antigen presenting cells with intense phagocytic activity, strategically distributed in tissues and cavities. These cells are capable of responding to a wide variety of innate inflammatory stimuli, many of which are signaled ...
Alma M. Astudillo   +5 more
doaj   +1 more source

Studies on seminal prostaglandins [PDF]

open access: yes, 1979
The lipid fraction of human semen has been separated by LH 20 Sephadex chromatography and TLC and the resulting fractions analysed by GCMS. Evidence is presented for the existence in semen of several prostaglandins, including 19 -OH PG F₁α, 19-OH PG ...
Taylor, Philip Leslie
core   +3 more sources

Effects of prostaglandins on LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes.

open access: yesJournal of Lipid Research, 1988
The effects of prostaglandin (PG) E1, PGE2, the stable prostacyclin analogue Iloprost, and PGF2 alpha on low density lipoprotein (LDL) receptor activity and cholesterol synthesis were investigated in freshly isolated human mononuclear leukocytes ...
W Krone   +4 more
doaj   +1 more source

Expression and clinical implication of cyclooxygenase-2 and E-cadherin in oral squamous cell carcinomas

open access: yesCancer Biology & Therapy, 2020
Epithelial-Mesenchymal Transition (EMT) and angiogenesis are crucial events for development of aggressive and often fatal Oral Squamous Cell Carcinomas (OSCCs).
Angela Santoro   +12 more
doaj   +1 more source

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