Results 21 to 30 of about 32,037,930 (259)

Biochemical warfare on the reef: the role of glutathione transferases in consumer tolerance of dietary prostaglandins. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Despite the profound variation among marine consumers in tolerance for allelochemically-rich foods, few studies have examined the biochemical adaptations underlying diet choice. Here we examine the role of glutathione S-transferases (GSTs) in
Kristen E Whalen   +3 more
doaj   +1 more source

Perfil inflamatorio del humor acuoso tras tratamiento asistido por láser de femtosegundo en casos de catarata nuclear

open access: yesRevista Mexicana de Oftalmología, 2023
Objective: Femtosecond laser-assisted cataract surgery (FLACS) is a treatment with increasing popularity. However, inflammation generated by the laser remains a subject of research.
Claudia Palacio-Pastrana   +7 more
doaj   +1 more source

Choline Glycerophospholipid-Derived Prostaglandins Attenuate TNFα Gene Expression in Macrophages via a cPLA2α/COX-1 Pathway

open access: yesCells, 2021
Macrophages are professional antigen presenting cells with intense phagocytic activity, strategically distributed in tissues and cavities. These cells are capable of responding to a wide variety of innate inflammatory stimuli, many of which are signaled ...
Alma M. Astudillo   +5 more
doaj   +1 more source

Effects of prostaglandins on LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes.

open access: yesJournal of Lipid Research, 1988
The effects of prostaglandin (PG) E1, PGE2, the stable prostacyclin analogue Iloprost, and PGF2 alpha on low density lipoprotein (LDL) receptor activity and cholesterol synthesis were investigated in freshly isolated human mononuclear leukocytes ...
W Krone   +4 more
doaj   +1 more source

Expression and clinical implication of cyclooxygenase-2 and E-cadherin in oral squamous cell carcinomas

open access: yesCancer Biology & Therapy, 2020
Epithelial-Mesenchymal Transition (EMT) and angiogenesis are crucial events for development of aggressive and often fatal Oral Squamous Cell Carcinomas (OSCCs).
Angela Santoro   +12 more
doaj   +1 more source

Chemistry of Prostaglandins and Thromboxanes

open access: yes, 1977
The structures of several prostaglandins were determined during the early 1960’s. First, two biologically active compounds were isolated from sheep vesicular glands; these compounds were called PGE1 and PGF1α (for a review, see Ref. 1). Reduction of PGE1
Granström, E, Elisabeth Granström
core   +1 more source

Metabolism of Prostaglandins

open access: yes, 1977
The major initial steps in the degradation of the prostaglandins are the oxidation of the secondary alcohol group at C-15 and the reduction of the Δ13 double bond (for a recent review, see 1).
Granström, E, Elisabeth Granström
core   +1 more source

Conserved and species-specific oxylipin pathways in the wound-activated chemical defense of the noninvasive red alga Gracilaria chilensis and the invasive Gracilaria vermiculophylla

open access: yesBeilstein Journal of Organic Chemistry, 2012
Chemical defense of the invasive red alga Gracilaria vermiculophylla has been studied and compared to that of the noninvasive but related Gracilaria chilensis. Both species rely on a wound-activated chemical defense that makes them less attractive to the
Martin Rempt   +3 more
doaj   +1 more source

The induction of preterm labor in rhesus macaques is determined by the  strength of immune response to intrauterine infection.

open access: yesPLoS Biology, 2021
Intrauterine infection/inflammation (IUI) is a major contributor to preterm labor (PTL). However, IUI does not invariably cause PTL. We hypothesized that quantitative and qualitative differences in immune response exist in subjects with or without PTL ...
Monica Cappelletti   +11 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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