Results 291 to 300 of about 158,535 (386)

Hypothalamus Regulates Anabolic Metabolism of Articular Cartilage Superficial Chondrocytes through PGE2 Skeletal Interoception

Advanced Science, Volume 12, Issue 19, May 22, 2025.
Hypothalamus sympathetic norepinephrine inhibits regeneration of articular cartilage. Mechanical loading on bone during animal activity elevates PGE2 skeletal interoception to promote an anabolic renewal of the superficial membrane by downregulation of norepinephrine for articular cartilage proper thickness and integrity.
Ziyi Wang, Xuequan Han, Jiawen Xu, Weixin Zhang, Kalp Patel, Jinjian Zheng, Mei Wan, Junying Zheng, Xu Cao   +8 more
wiley   +1 more source

The effect of the intracervical administration of follicle stimulating hormone or luteinizing hormone on the levels of hyaluronan, COX2 and COX2 mRNA in the cervix of the nonpregnant ewe [PDF]

, 2016
Khalid, M, Leethongdee, S, Scaramuzzi, R J   +2 more
core   +1 more source

Multiple roles of the PGE2‐EP receptor signal in vascular permeability

British Journal of Pharmacology, 2014
Keisuke Omori, Taiki Kida, M. Hori, Hiroshi Ozaki, T. Murata   +4 more
semanticscholar   +1 more source

A Case Study of a Female Infant With Primary Hypertrophic Osteoarthropathy Demonstrates That Early Initiation of Celecoxib Slows but Does Not Prevent Symptom Progression

American Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT Primary Hypertrophic Osteoarthropathy (PHOAR1) is characterized by autosomal recessive loss of function variants in 15‐hydroxyprostaglandin dehydrogenase (HPGD) leading to digital clubbing, periostosis, pachydermia, and severe hyperhidrosis. HPGD catalyzes the first step of prostaglandin E2 (PGE2) degradation.
Kara Zehr, Morgan Buckley, Joshua W. Owens, Tomas Vanagunas, Patricia Vega Fernandez, Robert J. Hopkin, Amelle Shillington   +6 more
wiley   +1 more source

Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE₂ signaling pathway in mice. [PDF]

Front Immunol
Sakurai K, Chubachi S, Miyata J, Hamamoto J, Naganuma T, Shimada T, Otake S, Nakayama S, Irie H, Tsutsumi A, Kameyama N, Hegab AE, Shimoda M, Terai H, Yasuda H, Kanai Y, Arita M, Fukunaga K.   +17 more
europepmc   +1 more source

Advances in the Study of Metabolic Reprogramming in Gastric Cancer

Cancer Medicine, Volume 14, Issue 10, May 2025.
ABSTRACT Background Gastric cancer is one of the most prevalent malignancies of the digestive system and is associated with a poor prognosis, particularly in advanced metastatic stages, where the 5‐year survival rate is significantly low. Methods Recent research has demonstrated that metabolic reprogramming—including alterations in glucose, lipid, and ...
Yu Rong, Yuanyin Teng, Xiaoying Zhou
wiley   +1 more source

Oxylipins as canine sepsis indicators in vivo and in ex vivo skin organ culture model. [PDF]

Sci Rep
Biagini D, Di Franco C, Lazzarini G, Miragliotta V, Lomonaco T, Di Francesco F, Briganti A.   +6 more
europepmc   +1 more source

Role of PGE2 in maintenance of tonic contraction of guinea pig gallbladder

, 2003
Wenzhong Liu, Zuo-Liang Xiao, Piero Biancani, José Behar   +3 more
openalex   +1 more source

Dynamic compaction of human mesenchymal stem/precursor cells into spheres self‐activates caspase‐dependent IL1 signaling to enhance secretion of modulators of inflammation and immunity (PGE2, TSG6, and STC1)

Stem Cells, 2013
T. Bartosh, Joni H. Ylöstalo, N. Bazhanov, J. Kuhlman, D. Prockop   +4 more
semanticscholar   +1 more source

Lipid Metabolism in Gastrointestinal Malignancies: Exploring Dysregulation, Biomarkers, and Treatment Strategies

Cancer Medicine, Volume 14, Issue 10, May 2025.
ABSTRACT Background Gastrointestinal malignancies are a major public health concern worldwide, characterized by high incidence and mortality rates. Despite continuous advancements in existing treatment methods, overall survival rates remain low. Lipid metabolism plays a crucial role in the occurrence, progression, and treatment of gastrointestinal ...
Yan An, Huihui Song, Hongyan Qiu, Jun Jiang, Junfeng Shi   +4 more
wiley   +1 more source