Results 301 to 310 of about 133,795 (342)

PGE2 vs PGF2α in human parturition

Placenta, 2021
Prostaglandin E2 (PGE2) and F2α (PGF2α) are the two most prominent prostanoids in parturition. They are involved in cervical ripening, membrane rupture, myometrial contraction and inflammation in gestational tissues. Because multiple receptor subtypes for PGE2 and PGF2α exist, coupled with diverse signaling pathways, the effects of PGE2 and PGF2α ...
Wen-Jiao, Li, Jiang-Wen, Lu, Chu-Yue, Zhang, Wang-Sheng, Wang, Hao, Ying, Leslie, Myatt, Kang, Sun   +6 more
openaire   +2 more sources

Cancer immunity derailed: PGE2 misconducts cDC1s

Immunity, 2023
Type 1 conventional dendritic cells (cDC1s) are critical for CD8+ T cell-mediated tumor control. In this issue of Immunity, Bayerl et al.1 expose a mechanism leading to cancer progression where prostaglandin E2 induces dysfunctional cDC1s, which cannot coordinate CD8+ T cell migration and expansion.
Matthew Brown, Michelle A. Tran, Nina Bhardwaj   +2 more
openaire   +2 more sources

Intravaginal PGE2 in early abortion

Prostaglandins, 1974
Abstract Intravaginal PGE2 was administered to 10 women in early (less than 50 days) pregnancy. Complete abortion was effected in 8, an incomplete abortion in one and one was a failure. Significant systemic side effects were noted in all subjects. Urinary hCG excretion rates prior to and on the 2nd and 14th day after PGE2 showed a decrease in all ...
James R. Jones, Romeo J. Perez, William Bienart   +2 more
openaire   +2 more sources

Diminished PGE2 content, enhanced PGE2 release and defects in 3H-PGE2 transport in embryos from overtly diabetic rats.

Reproduction, fertility, and development, 2001
Diminished PGE2 levels in diabetic embryos are related to the development of malformations, and thus the aim of the present study was to determine whether PGE2 levels are modified in rat embryos cultured in diabetic serum during organogenesis, and if PGE2 content and release, and 3H-PGE2 uptake and release, are altered in incubated diabetic embryos ...
A, Jawerbaum, E T, Gonzalez, D, Sinner, C, Pustovrh, V, White, M A, Gimeno   +5 more
openaire   +2 more sources

Physiological and pathophysiological implications of PGE2 and the PGE2 synthases in the kidney

Prostaglandins & Other Lipid Mediators, 2018
Prostaglandin E2 (PGE2) is the most abundant prostanoid synthesized in the kidney and plays an important role in renal function. Physiologically, PGE2 regulates renal hemodynamics, water and sodium metabolism, blood pressure, and so on. As a well-known proinflammatory lipid mediator, PGE2 also substantially mediates renal injury under many ...
Jing, Wang, Min, Liu, Xiaoyan, Zhang, Guangrui, Yang, Lihong, Chen   +4 more
openaire   +2 more sources

PGE2, PGF2α and catecholaminesinpheochromocytoma

Prostaglandins, Leukotrienes and Medicine, 1982
In order to relate urinary prostaglandin excretion in pheochromocytoma /Ph/ to the pattern of noradrenaline /NA/, adrenaline /A/ and dopamine /D/, 14 patients with this disease were investigated during normal sodium intake. 20 healthy volunteers served as controls /C/. Urinary PGs were determined by RIA; NA, A and D were measured fluorometrically.
H. Ignatowska-Switalska, B. Wocial, W. Januszewicz, S. Filipecki   +3 more
openaire   +1 more source

PGE2-Gel intrazervikal versus PGE2-Vaginaltabletten: Indikationen, Erfolge und Nebenwirkungen

1988
Wahrend die Geburtseinleitung durch Oxytozin heute aus vielerlei Grunden in weit geringerem Umfang Anwendung findet, erlangt die Geburtsinduktion durch Zervixpriming mit lokaler Prostaglandinapplikation in jungerer Zeit sprunghaft zunehmendes Interesse.
F. Wolff, F. Neuhaus, A. Bolte
openaire   +1 more source

The placenta, PGE2 and parturition

Early Human Development, 1992
It is proposed that prostaglandin E2 (PGE2), secreted by the fetal placenta of the sheep, acts as a circulating regulator of the physiological function of many fetal organs (tissue) in a way analogous to catecholamines in the adult. The specificity of PGE2 action in different tissues is determined by three different receptor subtypes which regulate ...
openaire   +2 more sources

Preoperative cervical dilatation by oral PGE2

Contraception, 1976
Abstract In fifty healthy nulliparous women who underwent therapeutic abortion in the second trimester of pregnancy according to the method of Finks, cervical dilatation has been satisfactorily carried out with PGE 2 -tablets. The average dosage was 3mg.
A S, van den Bergh, E, Szabo, F E, Szontágh   +2 more
openaire   +2 more sources