Results 331 to 340 of about 158,535 (386)

Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction

Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.
ABSTRACT Excessive local inflammation is a common mechanism in many cardiovascular diseases (CVDs) such as hypertension, atherosclerosis and aortic aneurysms. In endothelial cells, inflammatory cytokines such as interferons, tumour necrosis factor alpha or interleukins increase oxidative stress and contractile prostanoids and the expression of adhesion
Ana M. Briones, Raquel Hernanz, Ana B. García‐Redondo, Cristina Rodríguez, Luis M. Blanco‐Colio, Almudena Val‐Blasco, María J. Alonso, Mercedes Salaices   +7 more
wiley   +1 more source

Human mesofluidic intestinal model for studying transport of drug carriers and bacteria through a live mucosal barrier.

Lab Chip
Wang CM, Oberoi HS, Law D, Li Y, Kassis T, Griffith LG, Breault DT, Carrier RL.   +7 more
europepmc   +1 more source

Participation of COX2/mPGES1/PGE2 in mouse and human endometrial stromal decidualization. [PDF]

BMC Vet Res
Wang PC, Liu J, Liu YF, Wu Y, Xue LL, Yang ZS.   +5 more
europepmc   +1 more source

Synthesis Methods and Therapeutic Journey of Carprofen and Its Derivatives: A Review

Chemical Biology &Drug Design, Volume 105, Issue 5, May 2025.
Although it is currently only used in veterinary therapy, carprofen proves to be a molecule with a versatile therapeutic potential for human pharmacotherapy. Moreover, the molecule is a target in the drug discovery process for the development of new bioactive compounds.
Carmen Limban, Diana Camelia Nuță, Miron Teodor Caproiu, Denisa Elena Dumitrescu, Șerban Iancu Papacocea, Alexandra Teodora Bordei, Florea Dumitrașcu   +6 more
wiley   +1 more source

Effect of Antibiotics on Clinical and Laboratory Outcomes After Mandibular Third Molar Surgery: A Double-Blind Randomized Clinical Trial. [PDF]

Antibiotics (Basel)
Soleymani F, Maté Sánchez de Val JE, Lijnev A, Makiabadi M, Martínez CP.   +4 more
europepmc   +1 more source

Palmatine inhibits TRIF-dependent NF-kB pathway against inflammation induced by LPS in goat endometrial epithelial cells [PDF]

, 2017
Cheng, Z R, Dong, S, Na, L, Sang, M, Wang, D, Yan, B, Yan, Z, Yang, H, Yang, Z, Zhang, S   +9 more
core  

Pathobiology and Regulation of Eosinophils, Mast Cells, and Basophils in Allergic Asthma

Immunological Reviews, Volume 331, Issue 1, May 2025.
ABSTRACT Eosinophilia is a hallmark of allergic disorders, including asthma, allergic rhinitis, and atopic dermatitis. The onset and maintenance of allergic inflammation in atopic adults involves the activation of selective hemopoietic processes and the migration of mature and immature eosinophils to allergic tissue, where these cells release mediators
Christiane E. Whetstone, Rand Amer, Samarah Maqbool, Tooba Javed, Gail M. Gauvreau   +4 more
wiley   +1 more source

Crosstalk Between nNOS/NO and COX-2 Enhances Interferon-Gamma-Stimulated Melanoma Progression. [PDF]

Cancers (Basel)
Patel A, Tong S, Roosan MR, Syed B, Awasthi A, Silverman RB, Yang S.   +6 more
europepmc   +1 more source

Integration of Single‐Cell RNA Sequencing Data and Bulk Sequencing Data to Characterise the CD8+ T‐Cell Exhaustion Mediated Immune Microenvironment in CRC

Journal of Cellular and Molecular Medicine, Volume 29, Issue 9, May 2025.
ABSTRACT CD8+ T cells are crucial for the anti‐tumour immune response, and their exhaustion contributes to poor prognosis and limited immunotherapy efficacy in colorectal cancer (CRC). In this study, we examined the immune microenvironment of CRC by integrating single‐cell RNA sequencing (scRNA‐seq) and bulk sequencing data.
Xiao‐Hua Ling, Gang Chen, Nan‐Nan Liu, Wen‐Xin Xu, Ming‐Feng Ding   +4 more
wiley   +1 more source

Distinct features of three clinical subtypes in 533 patients with primary hypertrophic osteoarthropathy. [PDF]

Orphanet J Rare Dis
Cai X, Yang X, Zhang P, Dou Z, Chen Z, Zhu C, Xu W, Wang X, Hong X, Zhang Z.   +9 more
europepmc   +1 more source