Results 51 to 60 of about 31,123 (251)

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

PGRS domain structures: Doomed to sail the mycomembrane

PLOS Pathogens, 2022
The impact of artificial intelligence (AI) in understanding biological processes is potentially immense. Structural elucidation of mycobacterial PE_PGRS is sustenance to unveil the role of these enigmatic proteins. We propose a PGRS “sailing” model as a smart tool to diffuse along the mycomembrane, to expose structural motifs for host interactions, and/
Berisio, Rita, Delogu, Giovanni
openaire   +4 more sources

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Design and Characterization of a Dual‐Mode Soft Robotic Flapping Propeller With Pneumatic Stiffness Modulation

Advanced Intelligent Systems, EarlyView.
A novel soft robotic propeller overcomes traditional efficiency‐flexibility tradeoffs via a hybrid pneumatic‐cable actuation strategy. This architecture enables active stiffness modulation with dual‐mode locomotion: tunable biomimetic swimming and earthworm‐inspired wriggling for confined spaces.
Jiazi Geng, Hua Shao, Yiyang Li, Lin Liang, Jinfeng Yang, Xianhong He, Fengran Xie   +6 more
wiley   +1 more source

Effect of indole-3-butyric acid concentration and cutting type on the propagation of Osmanthus fragrans

Technology in Horticulture
Osmanthus fragrans Lour. (sweet olive) is an evergreen shrub or small tree in the Oleaceae family with small and fragrant flowers. Stem cutting is the most commonly used asexual method for propagating O. fragrans. Different cutting types of O.
Yulong Chen, Lilin Chen, Donglin Zhang, Hsuan Chen, Ping Yu   +4 more
doaj   +1 more source

Distributed State Estimation for Mobile Robots in LiDAR Sensor Networks With Intermittent Inertial Measurements

Advanced Intelligent Systems, EarlyView.
A scalable distributed observer framework for LiDAR sensor networks is presented for robust tracking and pose estimation of mobile robots. By combining adaptable 3D detection, clustering‐based communication reduction, and intermittent inertial fusion, accurate and efficient estimation is achieved under occlusions and sensing constraints, with formally ...
Isabella Luppi, Ehsan Hashemi
wiley   +1 more source

Prevalence of raised mean platelet volume in patients of chronic plaque psoriasis

Journal of University Medical & Dental College
BACKGROUND & OBJECTIVE: Psoriasis is a systemic, chronic autoimmune inflammatory disorder. MPV is a useful metric for assessing platelet aggregation and activity.
Pakeeza Amna, Muhammad Shahid , Amara Safdar, M.Hussan Shahid   +3 more
doaj   +1 more source

Benchmarking Data‐Driven Control of Octopus‐Inspired Soft Arms in Underwater Environment

Advanced Intelligent Systems, EarlyView.
Underwater soft robots present safe, compliant interaction, yet reproducible control remains scarce. This work presents an open benchmark for octopus‐inspired arms: a smooth, velocity‐diverse data‐collection scheme produces a compact dataset to train a vanilla policy.
Muhammad Sunny Nazeer, Yasmin Tauqeer Ansari, Emanuele Solfiti, Baljinder Singh Bal, Matteo Lo Preti, Barbara Mazzolai, Cecilia Laschi   +6 more
wiley   +1 more source

Occupational Conditions and Well‐Being Among Informal Waste Pickers in Hong Kong: A Comparative Study of 2018 and 2023

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Informal waste pickers play a crucial role in urban recycling systems but often face precarious employment and systematic marginalization. This study examines the evolving demographic, occupational, and health trends of informal waste pickers in Hong Kong between 2018 and 2023.
Siu‐Ming Chan, Alan Tam, Heng Xu, Yu‐tian He, Yuen‐Ki Tang, Gum‐Ryeong Park, Wing‐Him Tang   +6 more
wiley   +1 more source