Results 121 to 130 of about 127,368 (296)

BIOTEX-biosensing textiles for personalised healthcare management. [PDF]

, 2010
Textile-based sensors offer an unobtrusive method of continually monitoring physiological parameters during daily activities. Chemical analysis of body fluids, noninvasively, is a novel and exciting area of personalized wearable healthcare systems ...
Mourier, Veronique, Luprano, Jean, J. LUPRANO, Costanzo, Daniele, Chuzel, Cyril, Di Francesco, Fabio, H. DE MONCUIT, Porchet, Jacques-André, K. T. LAU, N. TACCINI, V. MOURIER, I. CHARTIER, Lanier, Thierry, S. COYLE, M. G. TRIVELLA, Lau, King-Tong, C. BINI, DE ROSSI, DANILO EMILIO, Taccini, Nicola, O\u27Gorman, Donal, Bini, Christina, D. DIAMOND, N. MOYNA, Ridofi, Andrea, Revol-Cavalier, Frederic, Convert, Reynald, Coyle, Shirley, Chartier, Isabelle, Paradiso, Rita, Diamond, Dermot, J. A. PORCHET, S. SCHOUMACKER, R. PARADISO, Giovanna Trivella, Maria, De-Moncuit, Henri, A. RIDOLFI, Salvo, Pietro, Schoumacker, Sébastien, T. LANIER, Moyna, Niall, O'Gorman, Donal, De Rossi, Danilo, D. COSTANZO, C. CHUZEL, F. REVOL CHEVALIER   +44 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Fibers and fabrics for chemical and biological sensing [PDF]

, 2012
Wearable sensors can be used to monitor many interesting parameters about the wearer’s physiology and environment, with important applications in personal health and well-being, sports performance and personal safety.
Radu, Tanja, Coyle, Shirley, Lau, Kim, Benito-Lopez, Fernando, Diamond, Dermot   +4 more
core  

Optical fiber pH sensors based on layer-by-layer electrostatic self-assembled Neutral Red

, 2008
The layer-by-layer (LbL) electrostatic self-assembly technique was used for fabricating evanescent wave optical fiber pH sensors based on the colorimetric pH indicator Neutral Red (NR).
Matías, I. R., Goicoechea, J., Arregui, F. J., Zamarreño, C. R.   +3 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

New optical biosensors for uric acid and glucose

, 2008
This thesis describes the development of a microtiter plate assay for determination of uric acid. It also depicts the development, characterization and application of luminescence based optical biosensors for determination of uric acid and glucose ...
Schrenkhammer, Petra
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Semisynthetic fluorescent pH sensors for imaging exocytosis and endocytosis

Nature Communications, 2017
Existing pH-sensitive red fluorescent protein probes don’t perform well in monitoring exocytosis and endocytosis. Here, the authors combine organic dyes with self-labeling tags or antibodies to develop semisynthetic protein conjugates that can image ...
Magalie Martineau, Agila Somasundaram, Jonathan B. Grimm, Todd D. Gruber, Daniel Choquet, Justin W. Taraska, Luke D. Lavis, David Perrais   +7 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source