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Polyhydroxyalkanoate synthase (PhaC): The key enzyme for biopolyester synthesis
Current Research in Biotechnology, 2022 Polyhydroxyalkanoates (PHAs) are considered good candidates in replacing commercial petrochemical plastics in certain applications like single-use packaging since they are biodegradable, biocompatible and share similar properties with conventional ...
Min Fey Chek +2 more
exaly +3 more sources
Development of a highly degenerate primer-based molecular tool for detecting and classifying the four major classes of polyhydroxyalkanoate synthase (phaC) genes in bacteria [PDF]
Microbial Cell FactoriesPolyhydroxyalkanoate synthase (phaC) gene encodes for PHA synthase enzyme which plays a key role in PHA polymerisation. To screen, unknown bacterial strains for their potential to produce PHAs, the presence of phaC gene is essential.
Abdiqani Ibrahim Osman +3 more
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Engineering Bacillus megaterium for production of functional intracellular materials [PDF]
Microbial Cell Factories, 2017 Background Over the last 10–15 years, a technology has been developed to engineer bacterial poly(3-hydroxybutyrate) (PHB) inclusions as functionalized beads, for applications such as vaccines, diagnostics and enzyme immobilization. This has been achieved
Katrin Grage +2 more
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Scientific Reports, 2017 Polyhydroxyalkanoate (PHA) is a promising candidate for use as an alternative bioplastic to replace petroleum-based plastics. Our understanding of PHA synthase PhaC is poor due to the paucity of available three-dimensional structural information. Here we
Min Fey Chek +2 more
exaly +2 more sources
Asymmetric Open-Closed Dimer Mechanism of Polyhydroxyalkanoate Synthase PhaC
IScience, 2020 Summary: Biodegradable polyester polyhydroxyalkanoate (PHA) is a promising bioplastic material for industrial use as a replacement for petroleum-based plastics.
Min Fey Chek +2 more
exaly +3 more sources
Scientific ReportsXanthomonas oryzae pv. oryzae (Xoo) causes bacterial blight in rice. Polyhydroxyalkanoates (PHAs) consitute a diverse group of biopolyesters synthesized by bacteria under nutrient-limited conditions. The phaC gene is important for PHA polymerization.
Jun Tao, Qingbiao Xie
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Purification and Characterization of Polyhydroxyalkanoate Synthase from Extremely Halophilic Archaeon Haloferax mediterranei: Key Enzyme of Biodegradable Plastic Synthesis [PDF]
BioengineeringThe biosynthesis of polyhydroxyalkanoate (PHA) biopolymer is highly dependent on the activity of a key enzyme, PHA synthase (PhaC). The halophilic archaeon Haloferax mediterranei can accumulate large amounts of PHAs from different carbon sources under ...
Diya Alsafadi +2 more
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Cloning and Characterization of Polyhydroxybutyrate Synthase from Methylobacterium extorquens AM1 [PDF]
Журнал Сибирского федерального университета: Серия Биология, 2016 Multiple genes encoding putative PHB synthases (up to 5 in single strain) were found in Methylobacterium genomes. As a result of phylogenetic analysis proteins PhaC1, PhaC2, PhaC3 were identified as class I PHB synthases, PhaC4 proteins were identified ...
Svetlana A. Zamakhaeva +3 more
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Biology, 2023 Polyhydroxybutyrate (PHB) is a biocompatible and biodegradable polymer that has the potential to replace fossil-derived polymers. The enzymes involved in the biosynthesis of PHB are β-ketothiolase (PhaA), acetoacetyl-CoA reductase (PhaB), and PHA ...
Chanchanok Duangsri +9 more
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