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Phaeodactylum tricornutum as a Chassis: Insights into Its Potential, Challenges, and Perspectives [PDF]

open access: yesMarine Drugs
Phaeodactylum tricornutum is one of the most well-characterized microalgae and serves as a pivotal model diatom in global carbon fixation and the mediation of biogeochemical cycling of essential nutrients. Over the past few decades, the availability of a
Sen Wang   +10 more
doaj   +2 more sources

Physiological and metabolic fluctuations of the diatom Phaeodactylum tricornutum under water scarcity [PDF]

open access: yesFrontiers in Microbiology
Water scarcity is an escalating environmental concern. The model diatom, Phaeodactylum tricornutum, holds promise as a potential cell factory for the production of high-value natural compounds.
Ting-Bin Hao   +8 more
doaj   +2 more sources

Characterization of endogenous promoters of GapC1 and GS for recombinant protein expression in Phaeodactylum tricornutum

open access: yesMicrobiologyOpen, 2021
Although diatoms have been utilized as a cellular factory to produce biopharmaceuticals, recombinant proteins, and biofuels, only a few numbers of gene promoters are available. Therefore, the development of novel endogenous promoters is essential for the
Eun Ha Lee   +2 more
exaly   +2 more sources

Effect of RNA Demethylase FTO Overexpression on Biomass and Bioactive Substances in Diatom Phaeodactylum tricornutum [PDF]

open access: yesBiology
Phaeodactylum tricornutum is rich in bioactive substances, rendering it valuable in nutrition and medicine. Epigenetic editing mediated by human RNA demethylase FTO can significantly increase the yields of rice and potato and offers significant potential
Yanan Yang   +4 more
doaj   +2 more sources

Characterization of the VOC Promoter That Is Active Under Low-Salinity Conditions in the Diatom Phaeodactylum tricornutum [PDF]

open access: yesMarine Drugs
Microalgae such as Phaeodactylum tricornutum are promising cell biofactories for the production of high-value molecules, including monoclonal antibodies (mAbs). However, to date, the production of mAbs in P.
Charlotte Toustou   +3 more
doaj   +2 more sources

Telomere-to-telomere genome assembly of Phaeodactylum tricornutum [PDF]

open access: yesPeerJ, 2022
Phaeodactylum tricornutum is a marine diatom with a growing genetic toolbox available and is being used in many synthetic biology applications. While most of the genome has been assembled, the currently available genome assembly is not a completed ...
Daniel J. Giguere   +8 more
doaj   +2 more sources

The complete mitochondrial genome of Antarctic Phaeodactylum tricornutum ICE-H

open access: yesMitochondrial DNA. Part B. Resources, 2020
In this study, the complete mitochondrial genome (mtDNA) of the Antarctic Phaeodactylum tricornutum ICE-H was sequenced using Illumina NovaSeq PE150. The circular mtDNA was 77055 bp in size and encodes 60 genes, contains 24 tRNA genes, 34 protein-coding ...
Lina Liu   +4 more
doaj   +1 more source

Comparison of different lipid extraction procedures applied to three microalgal species

open access: yesEnergy Reports, 2020
The increase in the world’s energy demand has contributed to the emergence of new sustainable energy sources, such as microalgae, with their great potential to provide biofuels and other high value co-products for the food and health’s markets.
M. Gorgich   +4 more
doaj   +1 more source

The complete chloroplast genome of Phaeodactylum tricornutum ICE-H isolated from the Antarctic sea ice

open access: yesMitochondrial DNA. Part B. Resources, 2020
Phaeodactylum tricornutum ICE-H is a single-cell eukaryotic alga that can grow in the extreme Antarctic environment. The complete chloroplast genome of Phaeodactylum tricornutum ICE-H was assembled with the Illumina sequencing. The chloroplast genome was
Dan Li   +5 more
doaj   +1 more source

Enhanced pyruvate metabolism in plastids by overexpression of putative plastidial pyruvate transporter in Phaeodactylum tricornutum

open access: yesBiotechnology for Biofuels, 2020
Background The development of microalgal strains for enhanced biomass and biofuel production has received increased attention. Moreover, strain development via metabolic engineering for commercial production is being considered as the most efficient ...
Seungbeom Seo   +5 more
doaj   +1 more source

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