Results 11 to 20 of about 8,870 (219)

Phaeodactylum tricornutum: A Diatom Cell Factory. [PDF]

Trends in Biotechnology, 2020
A switch from a petroleum-based to a biobased economy requires the capacity to produce both high-value low-volume and low-value high-volume products. Recent evidence supports the development of microalgae-based microbial cell factories with the objective
Thomas O. Butler, R. Kapoore, S. Vaidyanathan   +2 more
semanticscholar   +5 more sources

Optimizing CRISPR/Cas9 for the Diatom Phaeodactylum tricornutum

Frontiers in Plant Science, 2018
CRISPR/Cas9 is a powerful tool for genome editing. We constructed an easy-to-handle expression vector for application in the model organism Phaeodactylum tricornutum and tested its capabilities in order to apply CRISPR/Cas9 technology for our purpose. In
Daniel Stukenberg, Stefan Zauner, Gianluca Dell’Aquila, Uwe G. Maier, Uwe G. Maier   +4 more
doaj   +3 more sources

Effects of Different pH Levels on the Structural and Functional Properties of Proteins of Phaeodactylum tricornutum [PDF]

Molecules
Phaeodactylum tricornutum is identified by its capacity for rapid growth, reproduction, and in vitro cultivation, as well as the presence of a range of high-value active compounds, including proteins, with potential food applications.
Yanli Wang, Laijing Zhu, Zhunyao Zhu, Meng Liu, Xiangzhong Zhao   +4 more
doaj   +2 more sources

RNA Editing Analysis Reveals Methyl Jasmonic Acid Regulation of Fucoxanthin and Fatty Acid Metabolism in Phaeodactylum tricornutum [PDF]

Marine Drugs
Phaeodactylum tricornutum is a marine diatom with significant biotechnological potential, particularly in producing high-value bioactive compounds such as fucoxanthin and unsaturated fatty acids, which possess significant pharmaceutical and nutraceutical
Sihui Huang, Hao Liu, Ruihao Xu, Wangchang Li, Han Yang, Xinlei Bao, Yuqing Hang, Yifu Gong, Yuxiang Zhao   +8 more
doaj   +2 more sources

Characterization of the VOC Promoter That Is Active Under Low-Salinity Conditions in the Diatom Phaeodactylum tricornutum [PDF]

Marine Drugs
Microalgae such as Phaeodactylum tricornutum are promising cell biofactories for the production of high-value molecules, including monoclonal antibodies (mAbs). However, to date, the production of mAbs in P.
Charlotte Toustou, Carole Plasson, Marie-Christine Kiefer-Meyer, Muriel Bardor   +3 more
doaj   +2 more sources

Phaeodactylum tricornutum: An established model species for diatom molecular research and an emerging chassis for algal synthetic biology

Journal of Phycology, 2023
Diatoms are prominent and highly diverse microalgae in aquatic environments. Compared with other diatom species, Phaeodactylum tricornutum is an “atypical diatom” displaying three different morphotypes and lacking the usual silica shell. Despite being of
M. Russo, Alessandra Rogato, M. Jaubert, B. Karas, A. Falciatore   +4 more
semanticscholar   +1 more source

Bioengineering of the Marine Diatom Phaeodactylum tricornutum with Cannabis Genes Enables the Production of the Cannabinoid Precursor, Olivetolic Acid

International Journal of Molecular Sciences, 2023
The increasing demand for novel natural compounds has prompted the exploration of innovative approaches in bioengineering. This study investigates the bioengineering potential of the marine diatom Phaeodactylum tricornutum through the introduction of ...
Fatima Awwad, Elisa Fantino, Marianne Héneault, Aracely Maribel Diaz-Garza, Natacha Mérindol, Alexandre Custeau, Sarah-Eve Gélinas, Fatma Meddeb-Mouelhi, Jessica Li, J. Lemay, B. Karas, I. Desgagné-Penix   +11 more
semanticscholar   +1 more source

Physiochemical and molecular responses of the diatom Phaeodactylum tricornutum to illumination transitions

Biotechnology for Biofuels and Bioproducts, 2023
Background Light is a key regulatory factor for photosynthesis and metabolism of microalgae. The diatom Phaeodactylum tricornutum is capable of exhibiting metabolic flexibility in response to light fluctuations.
W. Ding, Y. Ye, Lihua Yu, Meijing Liu, Jin Liu   +4 more
semanticscholar   +1 more source

Fucoxanthin from microalgae Phaeodactylum tricornutum inhibits pro-inflammatory cytokines by regulating both NF-κB and NLRP3 inflammasome activation

Scientific Reports, 2021
Pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α are mediated by the activation of various kinds of signaling pathways in the innate immune system. Particularly, NF-κB and NLRP3 inflammasome signaling are involved in the production and secretion
A-Hyeon Lee, Hye-Yoon Shin, Jong-Hwi Park, S. Koo, Sang Min Kim, Seung-Hoon Yang   +5 more
semanticscholar   +1 more source

Observations on Phaeodactylum tricornutum [PDF]

Journal of General Microbiology, 1958
SUMMARY: Phaeodactylum tricornutum Bohlin was isolated from a marine tank at Woods Hole, Mass., U.S.A. It appeared to be identical with the Plymouth strain of ‘Nitzschia closterium forma minutissima’. Cells were of two characteristic types, oval and fusiform, each of which remained constant for many cell divisions in clonal culture.
J C, LEWIN, R A, LEWIN, D E, PHILPOTT
openaire   +2 more sources