Results 171 to 180 of about 531,900 (348)

Could bacteriophages be used as a novel pest management tool to control gut endosymbionts in Western Flower Thrips?

open access: yesFrontiers in Agronomy
Several species of Thysanoptera are considered agricultural pests, especially Frankliniella occidentalis (Western Flower Thrips, WFT). The damage WFT causes to plants can either be direct by feeding and oviposition activity or indirect by WFT serving as ...
Stephanie Krueger   +5 more
doaj   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao   +14 more
wiley   +1 more source

Direct Electron Microscopy Study on the Morphological Diversity of Bacteriophage Populations in Lake Plußsee [PDF]

open access: yes, 1993
Direct electron microscopy of bacteriophages adsorbed to a carbon film without prior enrichment by specific host strains or concentration by physical or chemical methods was used to study the morphological diversity of natural bacteriophage assemblages ...
Demuth, Jutta   +2 more
core   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

open access: yesAdvanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo   +5 more
wiley   +1 more source

Mutual exclusion between related phages [PDF]

open access: yes, 1952
The discovery of the breakdown of superinfecting phage needs to be supplemented by genetic tests to find out whether the phage whose nucleic acid is broken down is, indeed, unable to contribute genetic markers to the progeny.
Dulbecco, R.
core   +1 more source

CircRSU1 Activates the hnRNPA1/HIF‐1α/CD24 Signaling Axis, Promoting Stemness Features of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals circRSU1 with important oncogenic roles in hepatocellular carcinoma (HCC). CircRSU1, highly abundant in HCC, interacts with and stabilizes hnRNPA1 from ubiquitination and degradation. This stabilization facilitates hnRNPA1 binding to the internal ribosome entry site of HIF1A to increase HIF‐1α protein translation.
Shuting Xue   +14 more
wiley   +1 more source

Novel strategies for vancomycin-resistant Enterococcus faecalis biofilm control: bacteriophage (vB_EfaS_ZC1), propolis, and their combined effects in an ex vivo endodontic model

open access: yesAnnals of Clinical Microbiology and Antimicrobials
Background Endodontic treatment failures are predominantly attributed to Enterococcus faecalis (E. faecalis) infection, a Gram-positive coccus. E. faecalis forms biofilms, resist multiple antibiotics, and can withstand endodontic disinfection protocols ...
Toka A. Hakim   +6 more
doaj   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan   +17 more
wiley   +1 more source

Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design

open access: yesAdvanced Science, EarlyView.
Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao   +4 more
wiley   +1 more source

Epidemiological and comparative genomic analysis of pathogenic Glaesserella parasuis from livestock agriculture in Shandong, China

open access: yesFrontiers in Microbiology
Glaesserella parasuis (G. parasuis) is the causative agent of Glässer’s disease, posing a significant economic threat to the livestock agriculture. The present study aimed to investigate the prevalence of G.
Zetong Huang   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy