Results 171 to 180 of about 531,900 (348)
Several species of Thysanoptera are considered agricultural pests, especially Frankliniella occidentalis (Western Flower Thrips, WFT). The damage WFT causes to plants can either be direct by feeding and oviposition activity or indirect by WFT serving as ...
Stephanie Krueger +5 more
doaj +1 more source
Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao +14 more
wiley +1 more source
Direct Electron Microscopy Study on the Morphological Diversity of Bacteriophage Populations in Lake Plußsee [PDF]
Direct electron microscopy of bacteriophages adsorbed to a carbon film without prior enrichment by specific host strains or concentration by physical or chemical methods was used to study the morphological diversity of natural bacteriophage assemblages ...
Demuth, Jutta +2 more
core +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Mutual exclusion between related phages [PDF]
The discovery of the breakdown of superinfecting phage needs to be supplemented by genetic tests to find out whether the phage whose nucleic acid is broken down is, indeed, unable to contribute genetic markers to the progeny.
Dulbecco, R.
core +1 more source
This study reveals circRSU1 with important oncogenic roles in hepatocellular carcinoma (HCC). CircRSU1, highly abundant in HCC, interacts with and stabilizes hnRNPA1 from ubiquitination and degradation. This stabilization facilitates hnRNPA1 binding to the internal ribosome entry site of HIF1A to increase HIF‐1α protein translation.
Shuting Xue +14 more
wiley +1 more source
Background Endodontic treatment failures are predominantly attributed to Enterococcus faecalis (E. faecalis) infection, a Gram-positive coccus. E. faecalis forms biofilms, resist multiple antibiotics, and can withstand endodontic disinfection protocols ...
Toka A. Hakim +6 more
doaj +1 more source
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan +17 more
wiley +1 more source
Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design
Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao +4 more
wiley +1 more source
Glaesserella parasuis (G. parasuis) is the causative agent of Glässer’s disease, posing a significant economic threat to the livestock agriculture. The present study aimed to investigate the prevalence of G.
Zetong Huang +10 more
doaj +1 more source

