Results 171 to 180 of about 469,268 (356)
Biotechnology and Bioengineering, EarlyView.A novel puromycin linker for cDNA display was synthesized via SPAAC reaction. Its functionality was confirmed by recovering intact DNA after selection against EpCAM. The system also enabled the verification of bicyclic peptides during display, demonstrating its utility for constructing and screening structurally complex peptide libraries.
Simon Schneider +3 more
wiley +1 more source
Selection of porin and LPS mutants during infection by phage T4 facilitates the emergence of β-lactam resistance in Escherichia coli. [PDF]
NPJ Antimicrob ResistLe-Boulch J +3 more
europepmc +1 more source
Genetically Programmed Control of Overflow Metabolism
Biotechnology and Bioengineering, EarlyView.ABSTRACT Overflow metabolism is a highly undesirable phenomenon that occurs in virtually all cell factories. Although several schemes have been applied to avoid overflow metabolism, this problem remains far from being solved. In this study, a genetic sensor for detecting overflow metabolism was designed, and its substrate specificity and reversibility ...
Lærke M. Jensen +3 more
wiley +1 more source
Isolation and characterization of a novel lytic bacteriophage Ecolivirus Myo-P293 targeting avian pathogenic Escherichia coli. [PDF]
Arch VirolXu H +6 more
europepmc +1 more source
Biotechnology Progress, EarlyView.Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal +5 more
wiley +1 more source