Results 251 to 260 of about 531,900 (348)

Quantizing DNA Metallization for Site‐Defined Growth of Single Quantum Emitters

Small Structures, EarlyView.
Predictive design rules guide DNA origami‐templated synthesis of atomically precise silver nanoclusters. Controlled nucleation yields single emitters with nanometer registration and reproducible fluorescence signatures, paving the way toward programable quantum photonic architectures and nanoscale device integration.
Swati Tanwar, Zihui Wang, Lintong Wu, Arnab Chatterjee, Kenneth J. T. Livi, Krishanu Ray, Ishan Barman   +6 more
wiley   +1 more source

Receptor identification and in vivo efficacy of a lytic phage vB_EcoStr-FJ63A against colistin-resistant Escherichia coli. [PDF]

Vet Res
Xiao T, Wang C, Zhu X, Wang X, Fan Y, Jia X, Lv J, Chen T, Hao Z.   +8 more
europepmc   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

Phage cocktails: state-of-the-art technologies and strategies for effective design. [PDF]

FEMS Microbiol Rev
Kaneko T, Nakatsuka K, Tsuneda S.
europepmc   +1 more source

Inhibition of Targeted Bacterial Growth Using MazF‐Expressing Phagemids: A Novel Therapeutic Approach Based on Endoribonuclease Toxin Molecules

Microbiology and Immunology, EarlyView.
ABSTRACT The extensive and indiscriminate use of antibiotics, which are intended to halt bacterial growth or eliminate them, has unintentionally given rise to antimicrobial resistance (AMR), which is a critical threat to global health. In the pursuit of alternative solutions, researchers have focused on type II toxin–antitoxin systems prevalent within ...
Hana Hasegawa, Tatsuki Miyamoto, Rino Isshiki, Tomoyoshi Kaneko, Kenichi Takasugi, Naohiro Noda, Satoshi Tsuneda   +6 more
wiley   +1 more source

Comprehensive genome analysis uncovers the diversity of jumbo phages in the pig gut microbiome. [PDF]

Front Vet Sci
Wei C, Chen Z.
europepmc   +1 more source

Genetic engineering for SIT application: a fruit fly‐focused review

Insect Science, EarlyView.
Abstract Sterile insect technique (SIT) has become a key component of efficient pest control. Fruit fly pests from the Drosophilidae and Tephritidae families pose a substantial and overwhelmingly increasing threat to the agricultural industry, aggravated by climate change and globalization among other contributors.
Serafima Davydova, Danheng Yu, Angela Meccariello   +2 more
wiley   +1 more source

Phage-based biocontrol of <i>Salmonella</i> and <i>E. coli</i> in raw chicken filets: optimizing phage-based solutions to enhance food safety under cooled storing conditions. [PDF]

Front Microbiol
Berhilevych O, Peh E, Vahle JC, Plötz M, Kittler S.   +4 more
europepmc   +1 more source

Combination of bacteriophage-probiotics alleviates intestinal barrier dysfunction by regulating gut microbiome in a chick model of multidrug-resistant Salmonella infection. [PDF]

J Anim Sci Biotechnol
Choi Y, Kang A, Seo E, Lee DJ, Park J, Kim Y, Yu K, Yun CH, Jang KB, Kim WK, Shim K, Kang D, Kim Y.   +12 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source