Results 281 to 290 of about 469,268 (356)

Additional file 3 of Characterization of broad-host-range Salmonella phage GSP006 and its efficacy in controlling Salmonella Pullorum contamination in poultry feed and drinking water

Shenyu Pang, Hongyang Zhang, Xincong Liu, Jilai Wang, Shunyuan Pan, Xiangyu Kong, Jun Song, Dongyang Gao   +7 more
openalex   +1 more source

Enhanced exonuclease–Cas9 systems promote multiple nucleotide deletions with higher efficiency and broader targeting scope in plants

Journal of Integrative Plant Biology, EarlyView.
Cas9 preferentially generates small indels. By tethering an exonuclease and a DNA‐binding domain (DBD) to Cas9, the Exo‐DBD‐Cas9 system efficiently promotes multiple nucleotide deletions. These expanded deletions enable effective disruption of miRNA‐mediated regulation and relieve translational repression through targeted editing of 3′ untranslated ...
Rui Zhang, Xu Tang, Yao He, Wei Wang, Qiurong Ren, Yiping Qi, Yong Zhang   +6 more
wiley   +1 more source

Phage-antibiotic synergy restores β-lactam efficacy in MDR Klebsiella quasipneumoniae biofilms and suppresses resistance. [PDF]

J Biomed Sci
Tchatchiashvili T, Marquet M, Gabashvili E, Mirza KA, Lohde M, Brandt C, Ehricht R, Pletz MW, Makarewicz O.   +8 more
europepmc   +1 more source

Synergistic engineering of Casδ nuclease for robust genome editing

Journal of Integrative Plant Biology, EarlyView.
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge, Chenchen Peng, Yang Du, Ying Chen, Zilong Zhao, Meixia Yu, Huairu Feng, Yuyang Xie, Siwei Sun, Shengnan Liu, Beibei Xin, Haiming Zhao, Sen Wu, Chao Bian, Zhijia Yang, Jinsheng Lai, Jian Chen   +16 more
wiley   +1 more source

Isolation and therapeutic potential of phage vB_EcoM_GXW16 against a drug-resistant avian pathogenic Escherichia coli strain. [PDF]

Poult Sci
Xu T, Yang W, Cao J, Wei X, Liu H, Li Y, Pan S, Ali N, Si H.   +8 more
europepmc   +1 more source

Cold comfort for change: Stream mats as biological indicators of ecosystem processes in the McMurdo Dry Valleys, Antarctica

Journal of Phycology, EarlyView.
Abstract Glacier‐fed streams (GFSs) make ideal systems for studying climate‐related changes. Some of the best‐studied GFSs are found in the McMurdo Dry Valleys (MDVs) of Antarctica, one of the Earth's coldest and driest deserts. Despite their harsh and isolated nature, MDV GFSs represent an oasis of life in a landscape visually devoid of it, with ...
Tyler J. Kohler, Ian Hawes, Adrian Howkins, Lydia H. Zeglin, Mike N. Gooseff, Diane M. McKnight   +5 more
wiley   +1 more source

Synergistic Efficiency of a Novel Temperate Phage YF1204 and Amikacin Against Carbapenem-Resistant <i>Pseudomonas aeruginosa</i> and Its Biofilms. [PDF]

Microorganisms
Yang Y, Bin Yahia NM, Pan Y, Ran Z, Yang J, Yang Y, Li G.   +6 more
europepmc   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Cattle Immunization with T7 Phage-Displayed Whole-Tick Antigens Reduces <i>Amblyomma americanum</i> Feeding Efficiency and Blocks Larval Tick Hatching. [PDF]

Pathogens
Ansari MA, Gaithuma AK, Nguyen TT, Kim WTH, Bencosme-Cuevas E, Berry J, Fridley J, Lohmeyer K, Koziol ME, Mulenga A.   +9 more
europepmc   +1 more source

The Ti Plasmid‐Encoded VirJ Functions as a Lysyl‐Phosphatidylglycerol Hydrolase in Agrobacterium tumefaciens

Molecular Microbiology, EarlyView.
We identify the long‐known virulence factor VirJ as a lysyl‐phosphatidylglycerol (L‐PG) hydrolase. Like the chromosomally encoded virulence factor AcvB, it prevents excessive accumulation of L‐PG in the membrane, thereby maintaining efficient T‐DNA transfer via the Type IV secretion system (T4SS) in Agrobacterium tumefaciens.
Britta Lotz, Lina Brodskaia, Christiane Fritz, Stefanie Hebecker, Maike K. Tauchert, Jennifer Breisch, Dieter Jahn, Franz Narberhaus, Jürgen Moser, Meriyem Aktas   +9 more
wiley   +1 more source