Results 291 to 300 of about 531,900 (348)
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The arms race between bacteria and their phage foes
Nature, 2020Peter C Fineran
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Current Biology, 2023
In this Quick guide, Harding et al. introduce jumbo phages - the overlooked giants of the phage universe.
Kate R, Harding +2 more
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In this Quick guide, Harding et al. introduce jumbo phages - the overlooked giants of the phage universe.
Kate R, Harding +2 more
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Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review.
Lancet. Infectious Diseases (Print), 2022According to the latest reports from WHO, the incidence of antibiotic-resistant bacterial infections is increasing worldwide, resulting in increased morbidity and mortality and a rising pressure on health-care systems.
S. Uyttebroek +16 more
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Toxin-Antitoxin Systems as Phage Defense Elements.
Annual Review of Microbiology, 2022Toxin-antitoxin (TA) systems are ubiquitous genetic elements in bacteria that consist of a growth-inhibiting toxin and its cognate antitoxin. These systems are prevalent in bacterial chromosomes, plasmids, and phage genomes, but individual systems are ...
Michele LeRoux, M. Laub
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Molecular Microbiology, 1996
SummaryThere has recently been great interest in the use of the filamentous bacteriophage fd as a vehicle for the display of peptides and proteins. Phage libraries displaying random peptides up to 38 amino acids in length can be used (i) to select for ligands able to bind specific target molecules; (ii) to mimic nonāproteinaceous ligands; and (iii) as ...
H R, Hill, P G, Stockley
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SummaryThere has recently been great interest in the use of the filamentous bacteriophage fd as a vehicle for the display of peptides and proteins. Phage libraries displaying random peptides up to 38 amino acids in length can be used (i) to select for ligands able to bind specific target molecules; (ii) to mimic nonāproteinaceous ligands; and (iii) as ...
H R, Hill, P G, Stockley
openaire +2 more sources
2020
Often considered to be the most numerous and most diverse biological entities, phages are relatively simple forms of life. Despite this, phages have remarkably similar behaviors to those characterized in more complex organisms. When considering the biological development of phages from this perspective, new ideas and narratives can be explored to ...
Jimmy T. Trinh, Lanying Zeng
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Often considered to be the most numerous and most diverse biological entities, phages are relatively simple forms of life. Despite this, phages have remarkably similar behaviors to those characterized in more complex organisms. When considering the biological development of phages from this perspective, new ideas and narratives can be explored to ...
Jimmy T. Trinh, Lanying Zeng
openaire +1 more source
Phage and phage cocktails formulations
2023Antibiotic-resistant bacterial infection is a major global problem and can be life-threatening. Bacteriophages or phages can be substituted choice over traditional antibiotics treatments. Phages are natural obligate parasites viruses of bacteria, and they can infect and kill antibiotic-sensitive and -resistant bacteria.
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Drug Discovery Today, 2009
There is a renaissance of interest in the antimicrobial potential of phages as more pathogens become multiply antibiotic resistant. Phage therapy is not a new concept, and it is important to ask why it is not part of the current repertoire of western medicine despite the fact that it has been continuously and extensively used in Eastern Europe for ...
John N, Housby, Nicholas H, Mann
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There is a renaissance of interest in the antimicrobial potential of phages as more pathogens become multiply antibiotic resistant. Phage therapy is not a new concept, and it is important to ask why it is not part of the current repertoire of western medicine despite the fact that it has been continuously and extensively used in Eastern Europe for ...
John N, Housby, Nicholas H, Mann
openaire +2 more sources

