Results 271 to 280 of about 116,257 (347)

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles

open access: yesSmall, Volume 22, Issue 7, 2 February 2026.
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins   +10 more
wiley   +1 more source

Role of phage therapy in acute gastroenteritis. [PDF]

open access: yesJ Res Med Sci
Sabzali S   +3 more
europepmc   +1 more source

Bioswitches: Towards programmable, on‐demand control of therapeutic proteins

open access: yes
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Benedict Wolf   +2 more
wiley   +1 more source

Bacterial Expression of Gene‐Encoding DNA Origami Structures

open access: yesSmall Structures, Volume 7, Issue 2, February 2026.
Bacterial targeting via programmable DNA origami, varying in rigidity and compactness is unexplored. In transformation assays, origami reduces transformation efficiency compared to single‐stranded scaffolds. Structural features and surface modifications, however, improve transformation outcomes.
Verena Dobretzberger   +7 more
wiley   +1 more source

Crystal structure of Schistosoma mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state

open access: yesActa Crystallographica Section D, Volume 82, Issue 2, Page 140-150, February 2026.
Structural characterization of S. mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state and identifies a schistosome‐specific epitope.Schistosoma mansoni cathepsin D1 (SmCD1) has been shown to be an essential enzyme for helminth metabolism due to its role in haemoglobin degradation: a key amino‐acid ...
Kelly L. Parker   +7 more
wiley   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá   +5 more
wiley   +1 more source

B‐Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization

open access: yesAllergy, Volume 81, Issue 2, Page 513-523, February 2026.
IgH repertoire sequencing of a large atopic dermatitis cohort reveal reduced IgE somatic hypermutation and increased IgE diversity associated with food allergen sensitization. Presence of a dog during the first year of life is associated with increased IgE somatic hypermutation, possibly countering the effect of food sensitization.
Kirandeep K. Gill   +18 more
wiley   +1 more source

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