Results 271 to 280 of about 114,190 (344)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, Volume 599, Issue 23, Page 3417-3443, December 2025.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Recent insights on phage therapy against multidrug-resistant Acinetobacter baumannii. [PDF]

AMB Express
Elshamy AA, Kamal SK, Mahmoud MT, Elhasany AM, Shady AA, Mohamed SA, Abd-Elmaaboud HA, El-Awady NE, Mohamed RA, El-Mirghany SA, El-Hady SW, Abd-ElRahman MM, Aboshanab KM.   +12 more
europepmc   +1 more source

SKIN DYSBIOSIS IN ATOPIC DOGS: IS PHAGE THERAPY AN ALTERNATIVE TO ANTIBIOTICS?

Iva Šumonja, Tina Kotnik
openalex   +2 more sources

Engineering the Link: From Genome Interaction Maps to Functional Insight

Advanced Biology, Volume 9, Issue 12, December 2025.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen, Simon Westermann, Valeriia Smialkovska, Jan Mathony, Angelika Feldmann, Dominik Niopek   +5 more
wiley   +1 more source

Phage Therapy in Managing Multidrug-Resistant (MDR) Infections in Cancer Therapy: Innovations, Complications, and Future Directions. [PDF]

Pharmaceutics
Mafe AN, Büsselberg D.
europepmc   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

Advanced Healthcare Materials, Volume 14, Issue 32, December 19, 2025.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark, Fereshteh Bayat, Sara Rahmani, Mathura Thirugnanasampanthar, Taylor Kramer, Elise Schwarz, David Wilson, Jeffrey I. Weitz, Zeinab Hosseinidoust, Tohid F. Didar   +9 more
wiley   +1 more source

[Cost aspects and reimbursement requirements of phage therapy]. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Häckl D, Dillschneider J, Elsner C.
europepmc   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, Volume 37, Issue 49, December 10, 2025.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Beyond Antibiotics: Exploring the Potential of Bacteriophages and Phage Therapy. [PDF]

Phage (New Rochelle)
Biswas SK, Sumon MMH, Ahmed S, Ruma RA, Parvin A, Paul DK, Roy AK, Tang SS.   +7 more
europepmc   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, Volume 8, Issue 12, December 2025.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source