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Abstract Patients infected with life-threatening multi-drug resistant (MDR) bacteria have been treated with cocktails of bacteriophages. This is a complicated form of personalized medicine as the phages given to a patient have to be selected beforehand on the basis of their lytic capacity of the infecting bacteria.
Rob J. de Boer +2 more
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Rob J. de Boer +2 more
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Phage therapy pharmacology: calculating phage dosing.
Advances in applied microbiology, 2016Phage therapy, which can be described as a phage-mediated biocontrol of bacteria (or, simply, biocontrol), is the application of bacterial viruses-also bacteriophages or phages-to reduce densities of nuisance or pathogenic bacteria. Predictive calculations for phage therapy dosing should be useful toward rational development of therapeutic as well as ...
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Phage diversity, genomics and phylogeny
Nature Reviews Microbiology, 2020Frank Oechslin, Sylvain Moineau
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Phage Therapy for Antibiotic-Resistant Bacterial Infections
Annual Review of Medicine, 2022Graham F Hatfull, Rebekah M Dedrick
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Population and evolutionary dynamics of phage therapy
Nature Reviews Microbiology, 2004Bruce R Levin, James J Bull
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