Results 251 to 260 of about 40,342 (348)
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron +6 more
wiley +1 more source
Biofilm-forming capability of <i>Salmonella</i> isolates sourced from poultry production and farm environments in Great Britain. [PDF]
Oastler C +6 more
europepmc +1 more source
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova +5 more
wiley +1 more source
Complete genome sequences of the lytic bacteriophage PBM-3 and the avian pathogenic <i>Escherichia coli</i> strain PE144. [PDF]
Cherbuin JD +4 more
europepmc +1 more source
Insights into the catalytic mechanism of formate dehydrogenases from different microbial sources
This integrated study combines experimental enzyme kinetics with QM/MM simulations to map the catalytic mechanisms of four formate dehydrogenases at the atomic level. This approach reveals the key determinants of catalytic efficiency and guides the rational design of biocatalysts for effective CO2 reduction—a crucial step towards sustainable ...
Laura Legnani +8 more
wiley +1 more source
ABSTRACT Aim Bacterial biofilms around the apex are crucial in disease progression and persistence of apical periodontitis. While intracanal biofilms initiate infection, extraradicular biofilms contribute to treatment resistance and persistence. Thus, a comprehensive understanding of these biofilms may help elucidate mechanisms underlying persistent ...
Yoko Asahi +11 more
wiley +1 more source
Engineered Pseudomonas aeruginosa phages with quorum-quenching enzyme or depolymerase for inhibition of biofilm formation. [PDF]
Luo X +7 more
europepmc +1 more source

