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Host Genetic Determinants of SARS-CoV-2 Susceptibility in Transplant Recipients and Donor Candidates: A Multicohort Analysis of HLA Variation [PDF]

Biomedicines
Background: Host genetic variation plays a key role in susceptibility to SARS-CoV-2 infection. Human leukocyte antigen (HLA) variation influences antiviral immune responses; however, allele-level associations with SARS-CoV-2 infection have varied across ...
Makbule Nihan Somuncu, Mahmut Selman Yıldırım, Ayşe Gül Zamani, Zahide Aleyna Yılık, Sümeyye Sultan Var   +4 more
doaj   +2 more sources

Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing

Frontiers in Immunology, 2022
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang, Jielin Wang, Xuan You, Xuan You, Yanmin He, Yanmin He, Xiaozhen Hong, Xiaozhen Hong, Ji He, Ji He, Sudan Tao, Sudan Tao, Faming Zhu, Faming Zhu   +13 more
doaj   +1 more source

Bacteria Load Determination of the Intestinal Microbiota and Identification of Spiroplasma and Wolbachia in Anopheles gambiae

International Journal of Zoology, 2022
The gut microbiota of mosquitoes is composed of a range of microorganisms. Among its microorganisms, some affect the vectorial capacity of mosquitoes.
Haziz Sina, Kamirou Chabi-Sika, Razaki Ossè, Akim Socohou, Ibrahim A. Abibou, Hafiz Salami, Germain Gil Padonou, Adolphe Adjanonhoun, Lamine Baba-Moussa   +8 more
doaj   +1 more source

High resolution HLA-DRB1 analysis and shared molecular amino acid signature of DRβ1 molecules in Occult hepatitis B infection

BMC Immunology, 2022
Aim To investigate the association of human leukocyte antigen (HLA)-DRB1 alleles and the variations of polymorphic amino acid changes in DRβ1 chain in Shaanxi Han population with Occult hepatitis B infection (OBI).
Tianju Wang, Chunmei Shen, Hengxin Li, Liping Chen, Sheng Liu, Jun Qi   +5 more
doaj   +1 more source

An Integrated Perspective on Virulence-Associated Genes (VAGs), Antimicrobial Resistance (AMR), and Phylogenetic Clusters of Pathogenic and Non-pathogenic Avian Escherichia coli

Frontiers in Veterinary Science, 2021
Avian pathogenic Escherichia coli (APEC) is an important bacterial pathogen that causes avian colibacillosis and leads to huge economic losses in the poultry industry.
Seyede Elham Rezatofighi, Arash Najafifar, Mahdi Askari Badouei, Seyed Mostafa Peighambari, Mohammad Soltani   +4 more
doaj   +1 more source

Mapping the Human Leukocyte Antigen Diversity among Croatian Regions: Implication in Transplantation

Journal of Immunology Research, 2021
In the present study, HLA allele and haplotype frequencies were studied using the HLA data of 9277 Croatian unrelated individuals, typed using high-resolution methods for the HLA-A, -B, -C, and -DRB1 loci.
Zorana Grubic, Marija Maskalan, Katarina Stingl Jankovic, Marija Burek Kamenaric, Renata Zunec   +4 more
doaj   +1 more source

Machine learning identifies ferroptosis-related gene ANXA2 as potential diagnostic biomarkers for NAFLD

Frontiers in Endocrinology, 2023
IntroductionNon-alcoholic fatty liver disease (NAFLD), a major cause of chronic liver disease, still lacks effective therapeutic targets today. Ferroptosis, a type of cell death characterized by lipid peroxidation, has been linked to NAFLD in certain ...
Jingtong Qin, Peng Cao, Xuexuan Ding, Zeyao Zeng, Liyan Deng, Lianxiang Luo, Lianxiang Luo   +6 more
doaj   +1 more source

Kombucha Tea as a Reservoir of Cellulose Producing Bacteria: Assessing Diversity among Komagataeibacter Isolates

Applied Sciences, 2021
Bacterial cellulose (BC) is receiving a great deal of attention due to its unique properties such as high purity, water retention capacity, high mechanical strength, and biocompatibility.
Salvatore La China, Luciana De Vero, Kavitha Anguluri, Marcello Brugnoli, Dhouha Mamlouk, Maria Gullo   +5 more
doaj   +1 more source

Effect of Two Types of Thoracolumbosacral Brace (With and Without Sensors) on Electromyography Activity of Selected Muscles in People With Thoracic Kyphosis During Typing [PDF]

Ṭibb-i Tavānbakhshī, 2023
Background and Aims People suffer from neck pain, headache, kyphosis and back pain while working with the computer for a long time, which seems to increase day by day with the advancement of technology. The present study aims to investigate the effect of
AmirAli Jafarnezhadgero, Milad Piran Hamlabadi, Ebrahim Noorian   +2 more
doaj   +1 more source

Phenotypic and Genotypic Properties of Fluoroquinolone-Resistant, qnr-Carrying Escherichia coli Isolated from the German Food Chain in 2017

Microorganisms, 2021
Fluoroquinolones are the highest priority, critically important antimicrobial agents. Resistance development can occur via different mechanisms, with plasmid-mediated quinolone resistance (PMQR) being prevalent in the livestock and food area. Especially,
Katharina Juraschek, Carlus Deneke, Silvia Schmoger, Mirjam Grobbel, Burkhard Malorny, Annemarie Käsbohrer, Stefan Schwarz, Diana Meemken, Jens Andre Hammerl   +8 more
doaj   +1 more source