Results 91 to 100 of about 420,323 (395)
The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes. [PDF]
, 1989 Phagosomes were purified from human neutrophils ingesting Salmonella typhimurium opsonized with adsorbed normal human serum or with rabbit IgG. Constituents within the phagosome were endogenously labeled by supplying the cells with 125INa during ...
Albert, J +3 more
core
CD14+ CD15- HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure. [PDF]
, 2017 OBJECTIVE: Immune paresis in patients with acute-on-chronic liver failure (ACLF) accounts for infection susceptibility and increased mortality. Immunosuppressive mononuclear CD14+HLA-DR- myeloid-derived suppressor cells (M-MDSCs) have recently been ...
Adams, DH +14 more
core +2 more sources
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Advanced Functional Materials, EarlyView.Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu +6 more
wiley +1 more source
A Fully Unsupervised Instance Segmentation Technique for White Blood Cell Images [PDF]
arXiv, 2023 White blood cells, also known as leukocytes are group of heterogeneously nucleated cells which act as salient immune system cells. These are originated in the bone marrow and are found in blood, plasma, and lymph tissues. Leukocytes kill the bacteria, virus and other kind of pathogens which invade human body through phagocytosis that in turn results ...
arxiv
Role of target geometry in phagocytosis.
Proceedings of the National Academy of Sciences of the United States of America, 2006 Phagocytosis is a principal component of the body's innate immunity in which macrophages internalize targets in an actin-dependent manner. Targets vary widely in shape and size and include particles such as pathogens and senescent cells.
J. Champion, S. Mitragotri
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai +9 more
wiley +1 more source
Neurobiology of Disease, 2003 Microglia and macrophages express the αM/β2 integrin complement-receptor-3 (CR3/MAC-1; CD11b/CD18) and scavenger-receptor-AI/II (SRAI/II). Both can mediate myelin phagocytosis.
Fanny Reichert, Shlomo Rotshenker
doaj
Detection of CD33 expression on monocyte surface is influenced by phagocytosis and temperature [PDF]
, 2019 CD33 is a myeloid-associated marker and belongs to the sialic acid-binding immunoglobulin (Ig)-like lectin (Siglec) family. Such types of receptors are highly expressed in acute myeloid leukemia, which could be used in its treatment.
Baisaeng, Nuttakorn +7 more
core +1 more source
Phagocytosis of Microorganisms
Clinical Infectious Diseases, 1982 For its survival, the host depends on an elaborate internal defense system to protect against persistent invasion by pathogenic microorganisms. This system is composed primarily of cellular and humoral components of the circulatory system and includes the "professional" phagocytes (polymorphonuclear leukocytes, monocytes, and tissue macrophages ...
openaire +5 more sources
Phagocytosis: A Fundamental Process in Immunity
BioMed Research International, 2017 One hundred years have passed since the death of Élie Metchnikoff (1845–1916). He was the first to observe the uptake of particles by cells and realized the importance of this process for the host response to injury and infection.
C. Rosales, E. Uribe-Querol
semanticscholar +1 more source