Results 101 to 110 of about 420,323 (395)
Advanced Functional Materials, EarlyView.A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao +8 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2019 Myelin surrounding central nervous system (CNS) axons breaks down in multiple sclerosis (MS) and following traumatic axonal injury. Myelin-debris so produced is harmful to repair since it impedes remyelination in MS and the regeneration of traumatized ...
Fanny Reichert, Shlomo Rotshenker
doaj +1 more source
Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages. [PDF]
PLoS ONE, 2018 Allergic bronchopulmonary aspergillosis (ABPA) in asthma is a severe, life-affecting disease that potentially affects over 4.8 million people globally. In the UK, ABPA is predominantly caused by the fungus Aspergillus fumigatus. Phagocytosis is important
Nicola L D Overton +4 more
doaj +1 more source
Role of shape in particle-lipid membrane interactions: from surfing to full engulfment [PDF]
arXiv, 2023 Understanding and manipulating the interactions between foreign bodies and cell membranes during endo- and phagocytosis is of paramount importance, not only for the fate of living cells but also for numerous biomedical applications. This study aims to elucidate the role of variables such as anisotropic particle shape, curvature, orientation, membrane ...
arxiv
Dysregulation of of phospholipid-specific phagocytosis by B1 B cells in diet-induced obese mice [PDF]
, 2016 B1 B cells have received increasing attention recently due to their newly discovered phagocytic and microbicidal capabilities. Several studies have demonstrated that B1 cells can phagocytize polystyrene fluorescent particles, bacteria (Staphylococcus ...
Vo, Hung
core +1 more source
GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain
Journal of Clinical Investigation, 2018 The mechanisms of pain induction by inflammation have been extensively studied. However, the mechanisms of pain resolution are not fully understood. Here, we report that GPR37, expressed by macrophages (M&PHgr;s) but not microglia, contributes to the ...
S. Bang +5 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu +7 more
wiley +1 more source
SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging
Molecular Therapy: Nucleic Acids, 2021 Maintaining the health of the endothelium is of critical importance to prevention against cell aging. The current study was performed to clarify the role of sirtuin1 (SIRT1) in platelet phagocytosis in cell aging and identified its downstream molecular ...
Yong Lan +5 more
doaj
The origins of phagocytosis and eukaryogenesis [PDF]
Biology Direct, 2009 Abstract Background Phagocytosis, that is, engulfment of large particles by eukaryotic cells, is found in diverse organisms and is often thought to be central to the very origin of the eukaryotic cell, in particular, for the acquisition of bacterial endosymbionts including the ancestor of the mitochondrion.
Maxim Y Wolf +3 more
openaire +4 more sources
Scientific Reports, 2019 Phagocytosis is a process in which target cells or particles are engulfed and taken up by other cells, typically professional phagocytes; this process is crucial in many physiological processes and disease states.
D. Schulz +3 more
semanticscholar +1 more source