Results 131 to 140 of about 373,406 (347)
THE RELATIONSHIP OF M PROTEIN AND RESISTANCE TO PHAGOCYTOSIS IN THE BETA HEMOLYTIC STREPTOCOCCI [PDF]
, 1955 Myron Morris, C. V. Seastone
openalex +1 more source
Advanced Science, EarlyView.These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang +9 more
wiley +1 more source
Our Impressive Immune System: More Than a Defense [PDF]
, 2014 Most likely the immune system was put into place in the original human body design. We know from Exodus 20:11 and other verses that God completed His work of creation in six days.
Conrad, Jason, Gillen, Alan L.
core +1 more source
An experimental enquiry into the nature of the substance in serum which influences phagocytosis [PDF]
, 1905 George Dean
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Advanced Science, EarlyView.BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan +13 more
wiley +1 more source
Lifespan‐Regulated CAR‐Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy
Advanced Science, EarlyView.Using a tamoxifen‐inducible Hoxb8 system, proliferative bone marrow progenitors can be generated, which are subsequently engineered with an anti‐CEA CAR construct containing a suicide gene (iCas9) and differentiated into CAR‐macrophages. This method facilitates scale up the production of CAR‐macrophages.
Chuancheng Gao +8 more
wiley +1 more source
PHAGOCYTOSIS OF CRYPTOCOCCUS NEOFORMANS IN ANEMIC MICE [PDF]
, 1959 H. H. Gadebusch
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Advanced Science, EarlyView.Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser +11 more
wiley +1 more source
PHAGOCYTOSIS IN RELATION TO ARNETH'S CLASSIFICATION OF NEUTROPHILES [PDF]
, 1909 Joseph E. Pottenger
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Advanced Microfluidics for Single Cell‐Based Cancer Research
Advanced Science, EarlyView.Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro +10 more
wiley +1 more source