Results 161 to 170 of about 264,616 (357)

Nanotherapy for Neural Retinal Regeneration

open access: yesAdvanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu   +11 more
wiley   +1 more source

Osteosarcoma Cell‐Derived Migrasomes Promote Macrophage M2 Polarization to Aggravate Osteosarcoma Proliferation and Metastasis

open access: yesAdvanced Science, EarlyView.
Migrasomes are newly discovered organelles in migrating cells. This study finds that osteosarcoma cell‐derived migrasomes promote the tumor‐promoting phenotype of macrophages and further aggravate osteosarcoma malignant progression via milk fat globule‐EGF factor 8.
Wanshun Liu   +10 more
wiley   +1 more source

DNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells

open access: yesAdvanced Science, EarlyView.
DNA origami‐cyanine (Do‐Cy) nanocomplexes are synthesized to selectively image KRAS‐mutant pancreatic cancer cells in the highly desmoplastic tumors. This study shows that the Do‐Cy nanocomplexes are preferentially internalized by cancer cells over other stroma cells via KRAS‐dependent macropinocytosis.
Hye‐ran Moon   +7 more
wiley   +1 more source

Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang   +16 more
wiley   +1 more source

Modulation (Inhibition and Augmentation) of Complement Receptor-3-Mediated Myelin Phagocytosis

open access: yesNeurobiology of Disease, 2001
The removal of damaged myelin is central to repair after injury to axons and in autoimmune demyelinating diseases. Complement receptor 3 (CR3/MAC-1) plays a major role in mediating the phagocytosis of damaged myelin by macrophages and microglia.
Fanny Reichert   +3 more
doaj  

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

open access: yesAdvanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao   +4 more
wiley   +1 more source

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