Results 241 to 250 of about 264,616 (357)

THE ENHANCEMENT OF BACTERIAL PHAGOCYTOSIS BY SERUM [PDF]

open access: bronze, 1969
Richard B. Johnston   +3 more
openalex   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

open access: yesAdvanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua   +19 more
wiley   +1 more source

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

open access: yesAdvanced Science, EarlyView.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao   +16 more
wiley   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

open access: yesAdvanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li   +6 more
wiley   +1 more source

PLATELET PHAGOCYTOSIS AND AGGREGATION [PDF]

open access: bronze, 1965
Henry Z. Movat   +3 more
openalex   +1 more source

Temperature Relations in Phagocytosis [PDF]

open access: yesJournal of Bacteriology, 1946
Paul F. Clark   +2 more
openaire   +4 more sources

Elasticity‐Driven Nanomechanical Interaction to Improve the Targeting Ability of Lipid Nanoparticles in the Malignant Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee   +5 more
wiley   +1 more source

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