Results 241 to 250 of about 435,809 (335)

Real‐Time In Vivo Visualization of Tumor‐Associated Macrophage Reprogramming Using a Nitric Oxide‐Activatable NIR‐II Nanoinducer

Advanced Science, EarlyView.
Reprogramming tumor‐associated macrophages is a promising therapeutic strategy for solid tumors. Here, a nitric oxide (NO)‐activatable NIR‐II fluorescence/photoacoustic nanoinducer (I/E@M2pep) that simultaneously facilitates and visualizes the repolarization of TAMs to an M1‐like phenotype is reported, thereby enhancing anti‐tumor efficacy through M1 ...
Qian Chen, Meng Li, Tuanwei Li, Chen Yang, Xiaohu Yang, Hongchao Yang, Yejun Zhang, Chunyan Li, Qiangbin Wang   +8 more
wiley   +1 more source

Macrophage makeover extreme viral edition: mechanisms of immune subversion and therapeutic perspectives. [PDF]

J Gen Virol
Fremont-Debaene Z, Faure-Dupuy S.
europepmc   +1 more source

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Nature Genetics, 2018
Michael S. Haney, Christopher J. Bohlen, Christopher J. Bohlen, D. Morgens, James Ousey, Amira A. Barkal, C. Tsui, Braeden K. Ego, Roni Levin, Roarke A. Kamber, Hannah Y. Collins, Andrew Tucker, Amy Li, D. Vorselen, Lorenzo Labitigan, Emily Crane, E. Boyle, Lihua Jiang, Joanne Chan, Esther Rincón, W. Greenleaf, B. Li, M. Snyder, I. Weissman, J. Theriot, Sean R. Collins, B. Barres, M. Bassik   +27 more
semanticscholar   +1 more source

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

Advanced Science, EarlyView.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng, Ge Zhu, Siyu Sun, Wenbo Yao, Yuning Zhang, Yong‐Guang Yang, Tianmeng Sun   +6 more
wiley   +1 more source

CD71⁺ Red Blood Cells Mediate Increased Erythrophagocytosis and Reduce Monocyte Number in a Monocyte Suspension Assay. [PDF]

Scand J Immunol
Li W, Acker JP.
europepmc   +1 more source

Phagocytosis [PDF]

The American Naturalist, 1907
openaire   +1 more source

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Monocyte-derived macrophages and their roles in ischemic stroke. [PDF]

J Cereb Blood Flow Metab
Dufort C, Tian Q, Lu L, Tong Y, Du Z, Rios Sigler A, Mathys H, Leak RK, Wang M, Hu X.   +9 more
europepmc   +1 more source

Liver Kinase B1 in CD11c+ Cells Inhibits Fibrosis in Chronic Pancreatitis via the Oncostatin M Signaling

Advanced Science, EarlyView.
This study demonstrates significantly reduced Lkb1 expression in CD11c+ cells in chronic pancreatitis (CP) patients and animal models. Lkb1 deletion enhances CD11c+CD206+ macrophage infiltration and reprograms pancreatic stellate cells (PSCs) via OSM signaling.
Wenqing Zhang, Shan Guo, Yu Zhang, He Ren, Ke Lei, Chenyang Zhao, Qian Yu, Hongqing Luo, Yujing Xiao, Xiaoming Feng, Xiaoyu Li   +10 more
wiley   +1 more source

Ch25h/25HC axis orchestrates phagocytosis and lipid metabolism after intracerebral haemorrhage

Lawrence CB, Zhou R, Tapia V, Bennington A, Gao R, Elmes M, Lin I, Dai Z, Crilly S, Pot C, Allan S, Kasher P.   +11 more
europepmc   +1 more source