Results 251 to 260 of about 435,809 (335)

Spatial heterogeneity in microglia-complement crosstalk: Implications for synaptic pruning in Alzheimer's disease. [PDF]

Alzheimers Dement
Ye Q, Gao W, Feng J, Li X, Li J, Yang F, Li L, Zi M, Wu X, Gao H, Li H.   +10 more
europepmc   +1 more source

Macrophage Phenotype Detection Methodology on Textured Surfaces via Nuclear Morphology Using Machine Learning

Advanced Intelligent Discovery, EarlyView.
A novel machine learning approach classifies macrophage phenotypes with up to 98% accuracy using only nuclear morphology from DAPI‐stained images. Bypassing traditional surface markers, the method proves robust even on complex textured biomaterial surfaces. It offers a simpler, faster alternative for studying macrophage behavior in various experimental
Oleh Mezhenskyi, Kateryna Andriienkova, Tetyana Goldanova, Ezgi Antmen, Thibaut Soubrie, Nihal Engin Vrana   +5 more
wiley   +1 more source

TREM2 and microglial immunity in Alzheimer's disease: mechanisms, genetics, and therapeutic opportunities. [PDF]

Front Immunol
Wang T, Liu X, Wang X, Hua F, Yan L.
europepmc   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Integrated Functional and scRNA-Seq Analyses Reveal Convergence of M-CSF- and GM-CSF-Derived Macrophages Following IL-27 Polarization. [PDF]

Cells
Imamichi T, Yang J, Chen Q, Kariyawasam U, Marquez M, Higgins J, Metz J, Sharma HN, Baseler MW, Sui H.   +9 more
europepmc   +1 more source

PHAGOCYTOSIS

Cold Spring Harbor Symposia on Quantitative Biology, 1933
openaire   +1 more source

Establishment and multifaceted characterization of a graded spinal cord injury model based on graduated impact depth

Animal Models and Experimental Medicine, EarlyView.
We established a graded spinal cord injury (SCI) model based on graduated impact depth, which was subsequently characterized across multiple dimensions, including locomotor function, imaging, histology, and transcriptomic profiles. We further identified transcriptomic changes in graded SCI at different time points postinjury and investigated the ...
Gang Zhou, Yue Hu, Zhimin Li, Shiyuan Han, Yuejia Li, Yongning Li, Jun Gao   +6 more
wiley   +1 more source

Indole-acetaldehyde from Rothia mucilaginosa activates the PXR/NRF2 axis to enhance alveolar macrophage phagocytosis and protect against ARDS. [PDF]

Respir Res
Fan W, Tan T, Yang C, Cao Y, Jin C, Liu X, Shang K, Wang J, Xu J, Li Y.   +9 more
europepmc   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, EarlyView.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

C-di-AMP sensitizes colorectal cancer to CD47 antibodies by activating NF-κB to promote macrophage phagocytosis. [PDF]

Cell Commun Signal
Hao Y, Fan Y, He H, Zeng Z, Zong Y, Yang Z, Li B, Cheng L.   +7 more
europepmc   +1 more source