Results 251 to 260 of about 373,406 (347)
Using a dynamic, tri‐culture air‐blood barrier model, this study reveals that macrophage‐mediated transport governs micron‐sized particle translocation under cyclic strain. The process is highly size‐dependent that 2 µm particles are transported by macrophages, 0.2 µm particles diffuse passively, and 5 µm particles are effectively blocked.
Yongjian Li +3 more
wiley +1 more source
CD47/SIRPα pathways: Functional diversity and molecular mechanisms. [PDF]
Bhardwaj N, Chandra H, Singh A, Babu R.
europepmc +1 more source
Mechanotransduction in Shaping Immunity: Pathways, Crosstalk, and Pathophysiological Relevance
This review comprehensively summarizes the role of mechanotransduction in shaping immunity. It details how immune cells respond to biomechanical cues via mechanotransduction cascades and emphasizes the mechanical crosstalks within the immune microenvironment. The emerging significance of mechanoimmunology in both health and diseases is also highlighted.
Ruijiao Yan +7 more
wiley +1 more source
Neutrophils in Myocarditis: A Focus on the Secretory and Phagocytotic Functions. [PDF]
Jia L, Shen Y, Feng W, Mai R, Wang X.
europepmc +1 more source
Electron Microscopic Studies on the Mechanism of Vital Stain, as Compared with That of Phagocytosis
Harutaka Tanaka
openalex +2 more sources
Based on next‐generation sequencing data of retinitis pigmentosa (RP) patients and controls, this study identifies TRIM49 as a novel gene for autosomal recessive RP. TRIM49 is specifically expressed in the retinal pigment epithelium (RPE) of human retina.
Zhen Yi +17 more
wiley +1 more source
Metabolic reprogramming in efferocytosis. [PDF]
Yan Q +6 more
europepmc +1 more source
An Engineered Probiotic Consortium Based on Quorum‐Sensing for Colorectal Cancer Immunotherapy
This work develops an engineered probiotic consortium sensing pH, hypoxia, and lactate in the tumor microenvironment. It releases a lactate‐depleting enzyme (LdhA) and a PD‐L1 nanobody. In humanized mouse models (MC38 and HT‐29 tumors), it achieves durable oscillations, suppresses tumors, activates CD8+, CD4+, IFN‐γ+ T cells, and reduces Foxp3 ...
Yufei Guo +11 more
wiley +1 more source
Microbial trash to metabolic treasure. [PDF]
Dowdell AS, Colgan SP.
europepmc +1 more source

