Results 301 to 310 of about 420,323 (395)

Development and Recent Advances in SLIPT‐PM: A Chemogenetic Platform for Manipulating Signaling at the Plasma Membrane

open access: yesChemBioChem, Accepted Article.
Upon cell stimulation, mammalian cells activate various signaling proteins and lipids by recruiting their upstream regulators to the inner leaflet of the plasma membrane (PM), which in turn determines their cellular response. Therefore, artificially inducing protein translocation to the PM is an effective strategy for dissecting cell signaling networks
Shuya Ohira   +3 more
wiley   +1 more source

Circulating Monocytes Contribute to Erythrocyte Clearance in Polycythemia Vera. [PDF]

open access: yesInt J Mol Sci
Borges MD   +9 more
europepmc   +1 more source

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens [PDF]

open access: yes, 2010
A-Gonzalez   +50 more
core   +1 more source

Synthesis and Evaluation of Trehalose‐Based Mertansine Warheads for BCG Delivery of Anti‐Cancer Agents

open access: yesChemBioChem, Accepted Article.
Non‐muscle invasive bladder cancer (NMIBC) accounts for 75% of bladder cancer cases, with Bacillus Calmette‐Guérin (BCG) immunotherapy as the gold standard for high‐risk patients. BCG elicits a robust immune response but is limited by adverse effects and resistance. To enhance its efficacy, we developed a trehalose‐based conjugation strategy, tethering
Michael Grimmeisen   +10 more
wiley   +1 more source

PTEN inhibits scavenger receptor-mediated phagocytosis of methicillin-resistant Staphylococcus aureus. [PDF]

open access: yesImmunohorizons
Faneuff EE   +12 more
europepmc   +1 more source

SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin

open access: yesNature, 2017
Jun Chen   +16 more
semanticscholar   +1 more source

Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin   +5 more
wiley   +1 more source

Immunotherapy of endometrial cancer via CD47 blockade-mediated macrophage phagocytosis. [PDF]

open access: yesPNAS Nexus
Yucebas K   +10 more
europepmc   +1 more source

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