Results 81 to 90 of about 420,323 (395)
Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn. [PDF]
, 2000 Macrophage Fcgamma receptors (FcgammaRs) mediate the uptake and destruction of antibody-coated viruses, bacteria, and parasites. We examined FcgammaR signaling and phagocytic function in bone marrow-derived macrophages from mutant mice lacking the major ...
Crowley, MT +6 more
core
Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses
Frontiers in Immunology, 2019 Antiviral activities of antibodies may either be dependent only on interactions between the antibody and cognate antigen, as in binding and neutralization of an infectious virion, or instead may require interactions between antibody–antigen immune ...
M. Tay, K. Wiehe, J. Pollara
semanticscholar +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD
Respiratory Research, 2021 Background Lower airway bacterial colonisation (LABC) in COPD patients is associated with increased exacerbation frequency and faster lung function decline.
R. Singh +8 more
doaj +1 more source
Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. [PDF]
, 2004 Daily phagocytosis by the retinal pigment epithelium (RPE) of spent photoreceptor outer segment fragments is critical for vision. In the retina, early morning circadian photoreceptor rod shedding precedes synchronized uptake of shed photoreceptor ...
Brodie, Scott E +5 more
core +1 more source
Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation [PDF]
, 2012 Because of their outstanding physical properties, carbon nanotubes (CNTs) are promising new materials in the field of nanotechnology. It is therefore imperative to assess their adverse effects on human health.
Authier, Hélène +9 more
core +3 more sources
Autophagy and Macrophage Functions: Inflammatory Response and Phagocytosis
Cells, 2019 Autophagy is a conserved bulk degradation and recycling process that plays important roles in multiple biological functions, including inflammatory responses.
Ming-Yue Wu, Jiahong Lu
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Timely resolution of bacterial infections critically depends on phagocytosis of invading pathogens by polymorphonuclear neutrophil granulocytes, followed by neutrophil apoptosis and removal by macrophages. Neutrophils integrate cues from the
Meriem Sekheri +3 more
semanticscholar +1 more source
Advanced Biology, EarlyView.HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang +6 more
wiley +1 more source
PGE2 inhibits neutrophil phagocytosis through the EP2R–cAMP–PTEN pathway
Immunity, Inflammation and Disease, 2022 Prostaglandin E2 (PGE2) is a potent lipid mediator of inflammation that modulates immune cell function by binding to unique G protein‐coupled receptors (EP receptors). PGE2 production increases during microbial infection and inflammation.
Zixuan Wang +5 more
doaj +1 more source