Results 61 to 70 of about 84,513 (267)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
DiagnosticsBackground: To use the apparent diffusion coefficient (ADC) as reliable biomarkers, validation of MRI equipment performance and clinical acquisition protocols should be performed prior to application in patients.
Se Jin Choi +7 more
doaj +1 more source
Review of tissue-mimicking materials for anthropomorphic modeling of arterial vessels [PDF]
Digital DiagnosticsBACKGROUND: In computed tomographic angiography, anthropomorphic specimens made of tissue-mimicking materials are used to improve the diagnosis of pathological changes in arteries.
Dariya I. Abyzova, Maria R. Kodenko
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
BioengineeringMultiparametric ultrasound (mpUS) enhances prostate cancer (PCa) diagnosis by using multiple imaging modalities. Tissue-mimicking materials (TMM) phantoms, favoured over animal models for ethical and consistency reasons, were created using polyvinyl ...
Adel Jawli, Ghulam Nabi, Zhihong Huang
doaj +1 more source
Development of a skull phantom for the assessment of implant X-ray visibility
Current Directions in Biomedical Engineering, 2016 The paper presents the development and test of a skull phantom, which can be used for the assessment of the radiographic visibility of neurovascular implants. State of the art methods are based on specimens of the human skull. These are highly individual
Hoffmann Thomas +5 more
doaj +1 more source
Physical Review D, 2004 12 pages, revtex, 3 figures, 1 table, references ...
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
CT Lilun yu yingyong yanjiuAccurate measurements of electron density and effective atomic number are essential for precise imaging diagnosis and dose estimation in the multiparametric functional analysis of dual-energy computed tomography (CT).
Xinliang LU +4 more
doaj +1 more source