Results 71 to 80 of about 262,063 (357)

Induced sensorimotor brain plasticity controls pain in phantom limb patients

open access: yesNature Communications, 2016
The cause of pain in a phantom limb after partial or complete deafferentation is an important problem. A popular but increasingly controversial theory is that it results from maladaptive reorganization of the sensorimotor cortex, suggesting that ...
T. Yanagisawa   +10 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Phantom limb pain [PDF]

open access: yesBritish Journal of Anaesthesia, 2000
Phantom pain is experienced by 60% to 80% of patients following limb amputation but is only severe in about 5% to 10% of cases. The mechanisms underlying pain in amputees are not fully understood, but factors in both the peripheral and central nervous system play a role.
Nikolajsen, Lone   +1 more
openaire   +6 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

The Possibility for Iodine Concentration Determination in a Phantom with Known Titers of an Iodine-Containing Contrast Agent, by Using Dual-Energy Computed Tomography

open access: yesВестник рентгенологии и радиологии, 2020
Objective: to study the capabilities of single-source dual-energy computed tomography (DECT) in quantifying the concentration of iodine in solutions.Material and methods. Single-source DECT was performed using a phantom containing a set of 5 tubes with a
A. S. Chaban, V. E. Sinitsyn
doaj   +1 more source

Active promoters give rise to false positive ‘Phantom Peaks’ in ChIP-seq experiments

open access: yesNucleic Acids Research, 2015
Chromatin immunoprecipitation (ChIP) is widely used to identify chromosomal binding sites. Chromatin proteins are cross-linked to their target sequences in living cells.
D. Jain   +4 more
semanticscholar   +1 more source

Properties of singularities in the (phantom) dark energy universe [PDF]

open access: yes, 2005
The properties of future singularities are investigated in the universe dominated by dark energy including the phantom-type fluid. We classify the finite-time singularities into four classes and explicitly present the models which give rise to these ...
S. Nojiri, S. Odintsov, S. Tsujikawa
semanticscholar   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Evaluation of internal temperature of bioequivalent agar phantom in magnetic hyperthermia

open access: yesNihon Kikai Gakkai ronbunshu
Magnetic hyperthermia (MHT) is a promising cancer treatment that kills cancer cells by heating them, However, its clinical utilization is limited owing to challenges in temperature control and measurement.
Ryuhei KUBOTA, Koji FUMOTO
doaj   +1 more source

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