Microneedle suction cup patches, prepared using bionic Drosophila tarsal claws, can effectively treat bacterial infectious stomatitis by rapidly and efficiently leveraging multiple effects, including antibacterial and anti‐inflammatory properties, promotion of vasodilation, and active mechanical contraction of the wound.
Jiaqi Qin+6 more
wiley +1 more source
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang+6 more
wiley +1 more source
Pain modulation in amputees: Exploring conditioned pain modulation and its influencing factors on amputated and non-amputated sides: A cross-sectional study. [PDF]
Barbosa Franco S+7 more
europepmc +1 more source
The examination of amputees’ psychological well-being “in the mirror” of phantom pain [PDF]
Kinga Pongrácz
openalex +1 more source
A high‐strength pH‐responsive hydrogel‐forming microneedle integrates gradient solvent replacement to enhance the mechanical properties of the acrylonitrile‐acrylic acid copolymer network, ensuring robust transdermal penetration and long‐term drug release.
Hui Li+12 more
wiley +1 more source
(545) Novel prototype device combines massage therapy with components of mirror therapy to address phantom limb pain in lower-limb amputees [PDF]
Niki Munk+3 more
openalex +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
The effects of graded motor imagery and its components on phantom limb pain and disability in upper and lower limb amputees: a systematic review protocol [PDF]
Katleho Limakatso+2 more
openalex +1 more source
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang+8 more
wiley +1 more source
Real-Time MR-Guided Lumbosacral Periradicular Injection Therapy Using a 0.55 T MRI System: A Phantom Study. [PDF]
Saeed S+10 more
europepmc +1 more source