Results 161 to 170 of about 33,291 (265)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Phantom Image Elevation Explained

, 2016
A subjective experiment was conducted to identify frequency bands that produce the effect of phantom image elevation. Subjects judged the perceived image regions of phantom center images for a broadband pink noise burst and its octave bands with seven different loudspeaker base angles.
openaire  

Assessing the technical capability of a room- and a gantry-mounted kV imaging device for intra-fractional fluoroscopy during stereotactic lung radiotherapy at a C-arm linear accelerator. [PDF]

Phys Imaging Radiat Oncol
Jungreuthmayer H, Knäusl B, Arnold J, Buschmann M, Renner A, Schmid M, Georg D, Lechner W.   +7 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Improving patient treatment accuracy using transit dosimetry with Electronic Portal Imaging Device images and deep learning. [PDF]

Phys Imaging Radiat Oncol
Marini L, Mozzi C, Avanzo M, Lizzi F, Meattini I, Pirrone G, Retico A, Uwitonze E, Kraan AC, Talamonti C.   +9 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Imaging cell phone radiation in tissue mimics with hyperpolarized low-field MRI. [PDF]

Sci Adv
Ogier SE, Russek SE, Martinez JA, Betz KM, Stupic KF, Watterson WJ, Simons MT, Holloway CL, Biller JR, Srivastava DJ, Teixeira RPAG, Keenan KE.   +11 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Endoscopic iso-pathlength self-calibration for direction-resolved retrieval of tissue optical properties. [PDF]

J Biomed Opt
Ovadia N, Duadi H, Fixler D.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source