Results 211 to 220 of about 104,829 (282)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Neural networks for faster laser ultrasound tomography in tissue phantoms. [PDF]

Photoacoustics
Al Fuwaires A, Lukacs P, Pieris D, Davis G, Mulvana H, Tant K, Stratoudaki T.   +6 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Development and Initial Evaluation of 3D-printed High Resolution Brain Phantom for PET. [PDF]

IEEE Trans Radiat Plasma Med Sci
Lo C, Shanina E, Gravel P, Hu Y, Lucero SA, Martins S, Mulnix T, Fontaine K, Nejati SF, Sun X, Li H, Qi J, Cherry SR, Carson RE, Toyonaga T.   +14 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Tissue Strain Mapping via Magnetic Resonance Elastography Can Be Used to Detect Active Lesion Expansion. [PDF]

Magn Reson Med
Yin Z, Lake DS, Manduca A, Huston J, Ehman RL.   +4 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Roadmap for light interaction with biophotonic surfaces and their diverse applications. [PDF]

J Biomed Opt
Władziński A, Meglinski I, Bykov A, Gritsevich M, Kryuchkov M, Katanaev VL, Dragoi B, Pop N, Kwon J, Fernandes SN, Godinho MH, Chalkidis SG, Vougioukalakis GC, Bones AM, Wróbel MS, Karpienko K, Władzińska M, Sokołowski P, Novikova T, Ramella-Roman JC, Stergar J, Simončič U, Milanič M, Vuković N, Radovanović J, Demić A, Inđjin D, Gnyba M, Szczerska M.   +28 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Quantitative evaluation of spatially-variant deformations recovered by deep learning on clinical-like breast lesions. [PDF]

IEEE Trans Radiat Plasma Med Sci
Gao M, Raj J, Rizwan H, Barufaldi B, Krishnamoorthy S, Millardet M, Maidment ADA, Surti S, Matej S.   +8 more
europepmc   +1 more source