Results 231 to 240 of about 223,710 (297)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Ticept: Wideband Electrical Properties Tomography by Tissue Composition Assessment With Quantitative $$ {}^1 $$ H $$ {}^{23} $$ Na $$ {}^{39} $$ K Multinuclear MRI. [PDF]

Magn Reson Med
Barendsz LJC, Sumser K, Gerhalter T, Mestrom RMC, Nagel AM, Paulides MM.   +5 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Influence of phantom material on the depth-dose profile and radiation quality factor of 126 MeV antiprotons - a FLUKA Monte Carlo study. [PDF]

Radiat Environ Biophys
Chattaraj A, Selvam TP.
europepmc   +1 more source

Gravitational lensing in holonomy corrected spherically symmetric black holes with phantom global monopoles [PDF]

Faizuddin Ahmed
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Part-solid pulmonary nodule phantoms with realistic morphology and densities by stereolithography-based 3D-printing: from design to validation. [PDF]

Eur Radiol Exp
D'hondt L, Buytaert D, Kellens PJ, Snoeckx A, Bacher K.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modular breast and tumor perfusion phantoms for 4D dynamic contrast-enhanced dedicated breast CT. [PDF]

Med Phys
Goris LC, Gouma S, Pautasso JJ, Michielsen K, Sechopoulos I.   +4 more
europepmc   +1 more source

An Evaluation of Phantom Pain among Traumatic Lower Limb Amputees in Lahore

Maha Aslam, Samreen Sadiq, Izzat Hassan Rana, Bakhtawar Lashari, Dilawaiz Raza, Maheen Rehman   +5 more
openalex   +2 more sources