FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
A Novel Approach to Fabricate Early Keratoconus Phantom Models. [PDF]
Transl Vis Sci TechnolTong H, Wu M, Han J, Li L, Zhang H.
europepmc +1 more source
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Inter-phantom variability in digital mammography: implications for quality control. [PDF]
Eur Radiol ExpGennaro G +3 more
europepmc +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
FEBS Open Bio, EarlyView.A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra +17 more
wiley +1 more source
Precision and Accuracy of Dimensional Assessment of Luminal Contours by Commercially Available Quantitative Angiography Software as a Prerequisite to Angiography Based FFR and Other Derived Parametrics. [PDF]
Catheter Cardiovasc IntervTobe A +12 more
europepmc +1 more source
NMDAR‐Antibody Encephalitis Diagnosed With Primary Central Nervous System Lymphoma: A Case Series
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT N‐methyl‐D‐aspartate receptor‐antibody encephalitis (NMDAR encephalitis) is one of the most common forms of autoimmune encephalitis, with a paraneoplastic relationship described in approximately 38%. Primary central nervous system lymphoma (PCNSL) is a rare hematologic malignancy that is not often considered as the underlying neoplasm in this ...
Soo Hyun Ahn +4 more
wiley +1 more source
An open-source deep learning framework for respiratory motion monitoring and volumetric imaging during radiation therapy. [PDF]
Med PhysHindley N, Keall PJ.
europepmc +1 more source
Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion +15 more
wiley +1 more source