Results 1 to 10 of about 8,552 (200)
Beyond high cost: Pharmaceutic low-resource setting barriers to antibacterial access [PDF]
PLOS Global Public HealthIruka N Okeke +2 more
exaly +3 more sources
Targeted Therapy Evolution from Defining a Sub-population to Crossing Multi-indications [PDF]
Advanced Pharmaceutical BulletinPurpose: It tends not only to shed lights on an emerging classification framework of disease according to the shared molecular pathogenesis across various organs/tissues, but also to inspire more efficient paradigms of pharmaceutic innovation in a ...
Daohong Chen
doaj +2 more sources
DTMUV upregulates DDX17 expression to facilitate viral replication [PDF]
Veterinary ResearchDuck Tembusu virus (DTMUV) is a single-stranded positive-sense RNA virus that poses a serious threat to the poultry industry, and its infection mechanism remains incompletely understood. This study aimed to investigate the role of the host protein DDX17 (
Yuting Cheng +11 more
doaj +2 more sources
Research note: the putative nuclear localization signal of duck circovirus type 1 cap protein is critical for VLP assembly [PDF]
Poultry ScienceDuck circovirus type 1 (DuCV-1) threatens the duck industry globally, with no approved vaccines available. This study aimed to establish a prokaryotic expression system for DuCV-1 virus-like particle (VLP) and clarify the role of the putative nuclear ...
Xinnuo Lei +7 more
doaj +2 more sources
DDX17 and viral infection [PDF]
VirulenceDDX17 (DEAD-box RNA helicase 17) is an essential RNA helicase and regulatory ATPase in host cells, extensively involved in various cellular processes during viral infections, such as RNA splicing, transcriptional regulation, and post-transcriptional ...
Yuting Cheng +7 more
doaj +2 more sources
Temporal transcriptomic atlas reveals sequential engagement of classical and emerging regulated cell death pathways during PRRSV infection [PDF]
Frontiers in Veterinary SciencePorcine reproductive and respiratory syndrome virus (PRRSV) causes devastating economic losses through complex immunopathology, yet the molecular mechanisms orchestrating host cell fate remain elusive.
Shinuo Cao +5 more
doaj +2 more sources
Frontiers in Pharmacology, 2022 Depression is a common and serious mental disorder. Data on its pathogenesis remain unclear and the options of drug treatments are limited. Here, we explored the role of pyroptosis, a novel pro-inflammatory programmed cell death process, in depression as
Yuhui Chai +8 more
doaj +1 more source
Urban-Rural Difference in Adherence Treatment of Hypertensive Patients In South Sumatra Indonesia [PDF]
BIO Web of Conferences, 2023 Treatment adherence is essential for controlling blood pressure and preventing complications. The availability of information regarding factors related to adherence is needed to design appropriate interventions. However, this information is still limited.
Rikmasari Yopi +3 more
doaj +1 more source
Chinese Medicine, 2021 Background Chinese materia medica processing is a distinguished and unique pharmaceutical technique in Traditional Chinese Medicine (TCM) used for reducing side effects, and increasing or even changing therapeutic efficacy of the raw herbs.Changes in the
Zhe Li +8 more
doaj +1 more source
Advances in pharmaceutic managements of migraine
Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 Migraine is a neurovascular disorder with great burden so that effective abortive and preventive treatment is needed. Different from the previous choice of drugs based on clinical experience, the specific treatment targeting the pathogenesis of migraine ...
LI Yan⁃sheng
doaj +1 more source