Results 31 to 40 of about 1,571,136 (309)
Tyrosinase Inhibitory Activity of Methanolic Extract and Fractions from Green Seaweed Ulva lactuca
SqualenUlva lactuca, a widely available green seaweed, has demonstrated promising bioactivity as a tyrosinase inhibitor. This study aimed to evaluate the tyrosinase inhibitory activity of U. lactuca extracts and identify the active compounds responsible.
Mohamad Gazali +7 more
doaj +1 more source
Pharmaceutical Transformation Products Formed by Ozonation—Does Degradation Occur?
Molecules, 2023 The efficiency of an advanced oxidation process (AOP) using direct and indirect ozonation for the removal of pharmaceutical residues from deliberately spiked deionized water was examined.
Adi Zilberman, Igal Gozlan, Dror Avisar
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Pharmaceutical wastewater toxicity: An ignored threat to the public health
Sustainable EnvironmentPharmaceutical waste disposal is a significant problem for the global healthcare system. It poses a threat to water safety, which is already a challenge as 1 out of 3 people still lack access to safe drinking water.
Maryam S. Fakhri B. +7 more
doaj +1 more source
Mechanistic Research for the Student or Educator (Part I of II)
Frontiers in Pharmacology, 2022 Many discoveries in the biological sciences have emerged from observational studies, but student researchers also need to learn how to design experiments that distinguish correlation from causation. For example, identifying the physiological mechanism of
Rehana K. Leak, James B. Schreiber
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The regulation of Pharmaceutical Excipients [PDF]
, 2016 Pharmaceutical excipients are vital components of drug formulations and are generally considered pharmacologically inert. Control of excipient manufacturing and distribution is now considered a key priority by regulatory authorities and pharmaceutical ...
Vikrant Saluja, Bhupinder Singh Sekhon
core
Additive Manufacturing of Oral Tablets: Technologies, Materials and Printed Tablets
Pharmaceutics, 2021 Additive manufacturing (AM), also known as three-dimensional (3D) printing, enables fabrication of custom-designed and personalized 3D constructs with high complexity in shape and composition.
Alperen Abaci +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Insights into the Adsorption Performance of Emerging Contaminants on Granular Activated Carbon
Separations, 2023 Emerging contaminants are being detected at a high frequency, posing significant environmental and human health challenges. This study aimed to investigate the potential of using commercial granular activated carbon for adsorbing nine aqueous emerging ...
Sang-Hoon Lee, Namgyu Kim, Donghee Park
doaj +1 more source