Results 151 to 160 of about 4,704,220 (246)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Medication Errors Associated With Anticoagulants at a Tertiary Care Hospital in Saudi Arabia: A Retrospective Cohort Study

International Journal of Clinical Practice
Mona Alkredees, Tahani Alkredees, Khalid Ageeli, Rahaf Aljafel, Mohammed Najie, Amani Alwady, Arwa Gharsan, Bayan Alghamdi, Atheer Assiri, Rama Alsreaya, Hussam Kariri, Ali Zarea, Majid Ali, Aseel Alsraeya   +13 more
doaj   +1 more source

The development of an integrated system for the management of pharmaceutical and surgical consumable products across a group of private hospitals : innovation report [PDF]

Continued pressure to reduce costs and manage healthcare delivery in risk-based reimbursement environments, has, internationally, resulted in hospitals adopting different methods to manage pharmaceutical and surgical consumable products.
Van den Bergh, Dena
core  

Reactivity‐Guided Janus Graphene With Asymmetric Interfacial Electrostatics for Tunable Charge Transport

Advanced Materials, EarlyView.
Stepwise dual‐side functionalization creates covalent Janus graphene with chemically and electrostatically asymmetric interfaces. The resulting nonadditive surface‐potential response and pronounced charge‐transport modulation demonstrate a versatile route for tailoring the electronic properties of graphene.
Shishi Liu, Zhuting Hao, Mira Kreßler, Oguzhan Yücel, Lotte Polling, Adrián Dewambrechies, Wesley Pietsch, Philip Nickl, Felix Fels, Kevin Pagel, Markus R. Heinrich, Patryk Kusch, Kirill Bolotin, Xin Chen, Siegfried Eigler   +14 more
wiley   +1 more source

Methanesulfonic Acid as a Dual‐Role Reagent for Porous Polymer Network Design

Advanced Materials, EarlyView.
The design of porous polymer networks (PPNs) using methanesulfonic acid (MSA) as a dual‐role reagent facilitates the synthesis of robust PPNs for specific applications. It also makes the scale‐up process techno‐economically feasible because MSA functions simultaneously as both a solvent and a catalyst for the reaction.
Kelechi Festus, Arnab Ghosh, Ankit Mondal, Theresa Ariri, Suman Mandal, Ahana Sarkar, Urme Podder, Qingsheng Wang, Hong‐Cai Zhou   +8 more
wiley   +1 more source

Real-World Outcomes of a Non-Medical Switch to Adalimumab-Atto Biosimilar: Safety, Effectiveness, and Treatment Persistence in an Adult Saudi Tertiary Care Population

Biologics: Targets & Therapy
Alhanouf Almousa,1 Mohamed Ahmed,2 Rayd Abdulaziz Almehizia,1 Meshal Aldurayhim,1 Gamal Mohamed,3 Almutairdi Abdulelah,4,5 Yousef Binamer,5,6 Ahmed Alshaikh71Pharmaceutical Care Division, King Faisal Specialist Hospital and Research Center, Riyadh ...
Almousa A, Ahmed M, Almehizia RA, Aldurayhim M, Mohamed G, Abdulelah A, Binamer Y, Alshaikh A   +7 more
doaj  

Scalable Fabrication of Chemically Stabilized Gelatin Hydrogel Fibers by Thermal Drawing

Advanced Materials Interfaces, EarlyView.
Scalable processing of hydrogel fibers remains a major challenge. By coupling thermal drawing with Maillard chemistry, a transient viscous‐flow window is created that enables continuous fabrication of microstructured gelatin fibers tens of meters long, while continued in situ crosslinking during drawing stabilizes the fibers for physiological ...
Chaoqun Dong, Bastien Schyrr, Stella Laperrousaz, Hritwick Banerjee, Andreas Leber, Fabien Sorin   +5 more
wiley   +1 more source

Control of Bacterial Attachment on Macroporous PDMS/Paraffin SLIPS With Varying Lubricant Viscosity

Advanced Materials Interfaces, EarlyView.
Slippery liquid‐infused porous surfaces (SLIPS) prepared from macroporous PDMS, infused with medical‐grade paraffins, were systematically investigated regarding the correlation of viscosity, surface corrugation, bulk porosity, and bacterial resistance. Substrate porosity was found to dominate lubricant stabilization and the antifouling activity.
Regina Kopecz, Sabrina A. Böer, Onur Özcan, Axel Rosenhahn   +3 more
wiley   +1 more source

Enhanced Xylene Sensing Performance of Fe‐Doped NiO Nanosheet Arrays via In Situ Growth

Advanced Materials Interfaces, EarlyView.
Xylene is a hazardous volatile organic compound (VOC) widely present in industrial environments, and achieving sensitive and stable detection of xylene remains a significant challenge for gas sensors. Here, a one‐step hydrothermal route was employed to in situ grow p‐type Fe‐doped NiO nanosheet arrays on ceramic tubes for xylene detection.
Yinglin Wang, Yitong Jiang, Zhaohui Lei, Yantong Meng, Wanting Cui, Pengfei Cheng, Ye Tian, Bowen Fang, Xidong Hao, Shanfu Sun, Yiyang Xu, Ning Sun, Zhi Weng   +12 more
wiley   +1 more source

Two‐Way Shape Memory Polymer Composite Gripper for Adaptive Robotic Applications

Advanced Materials Technologies, EarlyView.
A two‐way shape memory polymer (SMP) composite is developed with intrinsic shape‐changing capability driven solely by temperature, eliminating external actuation loads. Embedding the SMP in a low‐stiffness elastomeric matrix enabled reversible transformations during heating and cooling cycles.
Aamna Hameed, Kamran Ahmed Khan
wiley   +1 more source