Results 191 to 200 of about 4,704,220 (246)

MZF1 Inhibits TGFβ‐1/SMAD Signaling by Transcriptionally Activating SnoN to Augment Tumorigenic Potential in Colon Cancer

Advanced Science, EarlyView.
This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng, Mengxi Huang, Yiting Wang, Hongyu Wang, Haimei Feng, Xiaoming Bai, Jie Chen, Ke Xu, Xiaoyuan Chu, Zengjie Lei   +9 more
wiley   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

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Pharmaceutical care

Pharmacy World and Science, 1996
Drug-treatment failures can be prevented by applying a Pharmaceutical Care system. Therapeutic outcome monitoring is such a system, which can be applied to the (drug) treatment of several diseases like asthma, diabetes and cardiovascular diseases. Pharmaceutical Care is an outcome oriented, cooperative, systematic approach to providing drug therapy ...
  +6 more sources

Planning for Pharmaceutical Care

American Journal of Health-System Pharmacy, 1993
The process for planning a pharmaceutical care practice model at the University of California-San Diego Medical Center (UCSDMC) is described. Pharmaceutical care is viewed as a health care need, analogous to medical care or dental care. Provision of such care requires that pharmacists have a generalist, rather than specialist, orientation and be held ...
M P, Lee, M D, Ray
openaire   +2 more sources

Critically Examining Pharmaceutical Care

Journal of the American Pharmaceutical Association (1996), 2002
In the past decade, growing numbers of practitioners worldwide have adopted pharmaceutical care as an integral component of pharmacy practice. Established models of pharmaceutical care can reduce the burden of preventable drug therapy problems, but this promise has not yet been realized. Although many challenges remain, the profession has key resources
Charles Doug, Hepler, Linda M, Strand, Dick, Tromp, Sumon, Sakolchai   +3 more
openaire   +2 more sources

Technology and Automation in Pharmaceutical Care

Journal of the American Pharmaceutical Association (1996), 1996
Pharmacy computer systems in the future will help pharmacists assess patients' medication needs, evaluate drug therapy, and manage patient information. Technology companies are developing systems for automatic dispensing and for distributing medications from nurses' stations in hospitals and long-term care facilities.
B G, Felkey, K N, Barker
openaire   +2 more sources

Establishing a Pharmaceutical Care Database

Journal of the American Pharmaceutical Association (1996), 1996
This article has presented basic tools for collecting, using, storing, and retrieving patient information needed for the delivery of pharmaceutical care in the community pharmacy, using case studies that illustrate the practical application of this material.
M R, de Bittner, R, Michocki
openaire   +2 more sources

Pharmaceutical care

2002
Terry L. Schwinghammer, Grace D. Lamsam
  +5 more sources

Provision of pharmaceutical care

American Journal of Health-System Pharmacy, 1990
R K, Elliott, K D, Crist
openaire   +2 more sources