An Analysis of Current Healthcare Proposals: Obama and McCain [PDF]
, 2008 The healthcare system of the U.S. is broken. The next opportunity for overwhelming healthcare system reform will be when the next president takes office.
Terrell, Dan
core +1 more source
DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut
Advanced Science, EarlyView.Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su +16 more
wiley +1 more source
Views, knowledge, and practices of hospital pharmacists about using clinical pharmacokinetics to optimize pharmaceutical care services: a cross-sectional study. [PDF]
BMC Health Serv Res, 2022 Shawahna R, Shraim N, Aqel R.
europepmc +1 more source
Tertiary Pharmaceutical Care Services Between Facts and Realities
Journal of Advance Research in Pharmacy & Biological Science (ISSN: 2208-2360), 2016 Pharmacy practice is dynamic, evolving and requires high level of drug knowledge in clinical judgment, decision making and advanced skills in actively and systematically identifying and resolving patients pharmacotherapy problems for desired outcomes to be achieved in patient care.
openaire +2 more sources
Advanced Science, EarlyView.This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche +21 more
wiley +1 more source
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Correction to: Views, knowledge, and practices of hospital pharmacists about using clinical pharmacokinetics to optimize pharmaceutical care services: a cross-sectional study. [PDF]
BMC Health Serv Res, 2022 Shawahna R, Shraim N, Aqel R.
europepmc +1 more source
Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis
Advanced Science, EarlyView.Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim +16 more
wiley +1 more source
PNAUM: integrated approach to Pharmaceutical Services, Science, Technology and Innovation
Revista de Saúde PúblicaThis paper describes the development process of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM – National Survey on Access, Use and Promotion of Rational Use of Medicines) based on an integrated approach ...
Carlos Augusto Grabois Gadelha +6 more
doaj +1 more source
Perceptions, Expectations, and Experience of Physicians About Pharmacists and Pharmaceutical Care Services in Pakistan: Findings and Implications. [PDF]
Front Pharmacol, 2021 Hayat K +10 more
europepmc +1 more source