Results 31 to 40 of about 484,997 (242)

A REVIEW ON SUPRAMOLECULAR CHEMISTRY IN DRUG DESIGN AND FORMULATION RESEARCH [PDF]

open access: yes, 2013
Supramolecular chemistry, other way called as intermolecular chemistry disclose the relationship of molecules with environment. It exploits while exposing the physicochemical phenomina that happens when two like or unlike molecules/ions/systems contact ...
Anbazhagan, S.   +3 more
core   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Precise Molecular Structures of Cysteine, Cystine, Hydrogen-Bonded Dicysteine, Cysteine Dipeptide, Glutathione and Acetyl Cysteine Based on Additivity of Atomic Radii [PDF]

open access: yes, 2011
Structures of molecules are usually represented by arbitrary line drawings, ball and stick or space filling models. In recent years, the author found that using the appropriate radii of atoms and ions, bond lengths in inorganic, organic and biomolecules ...
Raji Heyrovska
core   +1 more source

Ab initio prediction of the polymorph phase diagram for crystalline methanol. [PDF]

open access: yes, 2018
Organic crystals frequently adopt multiple distinct polymorphs exhibiting different properties. The ability to predict not only what crystal forms might occur, but under what experimental thermodynamic conditions those polymorphs are stable would be ...
Beran, Gregory JO, Červinka, Ctirad
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Using Molinspiration as a didactic complement into teaching subjects of Medicinal Chemistry [PDF]

open access: yes, 2016
Medicinal Chemistry has high rates of failure and abandonment at the beginning of the courses where this disciplines are taught, as occurs in pharmaceutical sciences.
Fonseca, Custódia
core  

Pharmaceutical Chemistry during 1908. [PDF]

open access: yesJournal of Industrial & Engineering Chemistry, 1909
n ...
openaire   +2 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Applying a Chemical Structure Teaching Method in the Pharmaceutical Analysis Curriculum to Improve Student Engagement and Learning

open access: yes, 2022
Pharmaceutical analysis, as the core curriculum of chemistry, chemical engineering and pharmaceutical engineering, contains broad and in-depth knowledge that leads to massive learning & teaching loads.
Cao, Jun   +4 more
core   +1 more source

Minutes of the Division of Pharmaceutical Chemistry [PDF]

open access: yesJournal of Industrial & Engineering Chemistry, 1912
n ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy