Results 21 to 30 of about 1,889,609 (335)

Incorporating Stories of Sedatives, Spoiled Sweet Clover Hay, and Plants from the Amazon Rainforest into a Pharmaceutical Chemistry Course To Engage Students and Introduce Drug Design Strategies

Journal of Chemical Education, 2018
This article describes three historical cases of drug discovery and how they were adapted as examples to teach chemical analysis to students pursuing a pharmacy (UK MPharm) and pharmaceutical sciences (BSc Pharmaceutical Sciences) degree.
E. Larrañeta
semanticscholar   +1 more source

Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro

Heliyon, 2019
A novel series of 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones were synthesized, using the ‘molecular hybridization approach’ and evaluated for anticancer efficacy.
Chandrabose Karthikeyan, Haneen Amawi, Charles R. Ashby, Jr., Vishwa M. Khare, Veronica Jones, N.S. Hari Narayana Moorthy, Piyush Trivedi, Amit K. Tiwari   +7 more
doaj   +1 more source

Silver nanoparticle synthesis by Acalypha wilkesiana extract: phytochemical screening, characterization, influence of operational parameters, and preliminary antibacterial testing

Heliyon, 2019
Single pot green synthesis of silver nanoparticles (AgNPs) was successfully carried out using medicinal plant extract of Acalypha wilkesiana via bottom-up approach. Five imperative operational parameters (pH, contact time, concentration, volume ratio and
Adewumi Oluwasogo Dada, Folahan Amoo Adekola, Fehintoluwa Elizabeth Dada, Adunola Tabitha Adelani-Akande, Micheal Oluwasesan Bello, Chidiogo Rita Okonkwo, Adejumoke Abosede Inyinbor, Abimbola Peter Oluyori, Adeniyi Olayanju, Kolawole Oluseyi Ajanaku, Charles Oluwaseun Adetunji   +10 more
doaj   +1 more source

Syntheses, physicochemical characterization, antibacterial studies on potassium morpholine dithiocarbamate nickel (II), copper (II) metal complexes and their ligands

Heliyon, 2019
Organic molecule dithiocarbamate transition metal complexes are novel and very attractive pharmaceutical targets for the management and control of antibiotic resistant bacteria. The direct reaction has synthesized new transition metal nickel (II), copper
Senthilkumar Balakrishnan, Senbagam Duraisamy, Murugan Kasi, Selvam Kandasamy, Rajesh Sarkar, Anbarasu Kumarasamy   +5 more
doaj   +1 more source

THE ROLE AND SIGNIFICANCE OF CHEMICAL DISCIPLINES IN THE TRAINING OF PHARMACISTS

Вестник Северо-Кавказского федерального университета, 2022
The high importance of high-quality training of specialists in the field of pharmacy for the protection of the health of Russian citizens is shown.
I. Ukleina, R. Petinov
doaj  

Polyethylene glycol (PEG) decorated graphene oxide nanosheets for controlled release curcumin delivery

Heliyon, 2019
Nowadays, the use of nanostructures in various medical and biological fields such as drug delivery in cancer treatment is increasing. Among the nanostructures, graphene oxide (GO) is an excellent candidate for drug delivery application because of its ...
Jalil Charmi, Hamed Nosrati, Jafar Mostafavi Amjad, Ramin Mohammadkhani, Hosein Danafar   +4 more
doaj   +1 more source

Design, synthesis, biological evaluation and molecular docking studies of novel 3-substituted-5-[(indol-3-yl)methylene]-thiazolidine-2,4-dione derivatives

Heliyon, 2018
Various thiazolidine-2,4-dione derivatives 3a-l possessing indole moiety were designed, synthesized using appropriate conventional heating as well as microwave irradiation methods.
K. Srikanth Kumar, A. Lakshmana Rao, M.V. Basaveswara Rao   +2 more
doaj   +1 more source

Recent Trends in Pharmaceutical Analytical Chemistry [PDF]

, 2021
This book covers the most recent research trends and applications of Pharmaceutical Analytical Chemistry. The included topics range from the adulteration of dietary supplements, to the determination of drugs in biological samples with the aim to ...

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QSAR study of anti-Human African Trypanosomiasis activity for 2-phenylimidazopyridines derivatives using DFT and Lipinski's descriptors

Heliyon, 2019
The quantitative structure-activity relationship (QSAR) of sixty 2-phenylimidazopyridines derivatives with anti-Human African Trypanosomiasis (anti-HAT) activity has been studied by using the density functional theory (DFT) and statistical methods. Becke'
Samir Chtita, Mounir Ghamali, Abdellah Ousaa, Adnane Aouidate, Assia Belhassan, Abdelali Idrissi Taourati, Vijay Hariram Masand, Mohammed Bouachrine, Tahar Lakhlifi   +8 more
doaj   +1 more source

Oxazolidinones as versatile scaffolds in medicinal chemistry

, 2023
Oxazolidinone is a five-member heterocyclic ring with several biological applications in medicinal chemistry. Among the three possible isomers, 2-oxazolidinone is the most investigated in drug discovery. Linezolid was pioneered as the first approved drug
Cauê Benito Scarim, Scarim, Cauê Benito [UNESP], Daniele Castagnolo, Fernandes, Guilherme Felipe Santos, Seong-Heun Kim, Jingyue Wu, Wu, Jingyue, Kim, Seong-Heun, Castagnolo, Daniele, Guilherme Felipe Santos Fernandes   +9 more
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