Results 181 to 190 of about 666,519 (246)
Some of the next articles are maybe not open access.
ChemInform Abstract: Pharmaceutical Cocrystals
ChemInform, 2011AbstractReview: 98 refs.
Ning Qiao +5 more
openaire +1 more source
Pharmaceutical Cocrystals of Niclosamide
Crystal Growth & Design, 2012Niclosamide (NCL) is an anthelmintic BCS class II drug of low solubility and high permeability. Pharmaceutical cocrystals of NCL were prepared with GRAS molecules, such as caffeine (CAF), urea (URE), p-aminobenzoic acid (PABA), theophylline (THPH), nicotinamide (NCT), and isonicotinamide (INA), to improve drug solubility. Neat grinding, wet granulation,
Palash Sanphui +2 more
openaire +1 more source
Pharmaceutical cocrystals and poorly soluble drugs
International Journal of Pharmaceutics, 2013In recent years cocrystal formation has emerged as a viable strategy towards improving the solubility and bioavailability of poorly soluble drugs. In this review the success of numerous pharmaceutical cocrystals for the improvement of the solubility and dissolution rates of poorly soluble drugs is demonstrated using various examples taken from the ...
Ranjit, Thakuria +5 more
openaire +2 more sources
Multicomponent pharmaceutical cocrystals: furosemide and pentoxifylline
Acta Crystallographica Section C Crystal Structure Communications, 2012The combination of the active pharmaceutical ingredients furosemide [4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid] and pentoxifylline [3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione] produces a 1:1 cocrystal, C12H11ClN2O5S·C13H18N4O3, (I), a 1:1 cocrystal hydrate, C12H11ClN2O5S·C13H18N4O3·H2O, (II), and a 1:1 cocrystal ...
Dmitrijs, Stepanovs, Anatoly, Mishnev
openaire +2 more sources
Drug Development and Industrial Pharmacy, 2020
Pharmaceutical cocrystals are still gaining the interest of the researchers due to their potential to alter physicochemical, mechanical, and pharmacokinetic properties of active pharmaceutical ingredients without negotiating therapeutic action.
P. Panzade, G. Shendarkar
semanticscholar +1 more source
Pharmaceutical cocrystals are still gaining the interest of the researchers due to their potential to alter physicochemical, mechanical, and pharmacokinetic properties of active pharmaceutical ingredients without negotiating therapeutic action.
P. Panzade, G. Shendarkar
semanticscholar +1 more source
Pharmaceutical Cocrystal Drug Products: An Outlook on Product Development.
TIPS - Trends in Pharmacological Sciences, 2018Active pharmaceutical ingredients (APIs) are most commonly formulated and delivered to patients in the solid state. Recently, an alternative API solid-state form, namely the pharmaceutical cocrystal, has witnessed increasing academic and industrial ...
R. Shaikh +3 more
semanticscholar +1 more source
, 2020
In order to give full play to the superiority of cocrystallization techniques to overcome biopharmaceutical limitations in vitro and ameliorate pharmacokinetic properties in vivo together with heightening the antitumor abilities of the anticancer drug 5 ...
Yueming Yu +6 more
semanticscholar +1 more source
In order to give full play to the superiority of cocrystallization techniques to overcome biopharmaceutical limitations in vitro and ameliorate pharmacokinetic properties in vivo together with heightening the antitumor abilities of the anticancer drug 5 ...
Yueming Yu +6 more
semanticscholar +1 more source
Crystal research and technology (1981)
Pharmaceutical cocrystal technology has gained significant attention for its potential to enhance drug performance, particularly by improving solubility and bioavailability.
Yinxin Yang, Jie Lu
semanticscholar +1 more source
Pharmaceutical cocrystal technology has gained significant attention for its potential to enhance drug performance, particularly by improving solubility and bioavailability.
Yinxin Yang, Jie Lu
semanticscholar +1 more source
2017
The aim of this project is to improve cocrystal screening and solubility prediction methods.
openaire +1 more source
The aim of this project is to improve cocrystal screening and solubility prediction methods.
openaire +1 more source
Solubility Advantage of Pharmaceutical Cocrystals
Crystal Growth & Design, 2009Pharmaceutical cocrystals can improve solubility, dissolution, and bioavailability of poorly water soluble drugs. However, true cocrystal solubility is not readily measured for highly soluble cocrystals because they can transform to the most stable drug form in solution.
David J. Good, Naír Rodríguez-Hornedo
openaire +1 more source