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Nevirapine Pharmaceutical Cocrystal: Design, Development and Formulation
Drug Delivery Letters, 2019The top approach to deliver poorly soluble drugs is the use of a highly soluble form. The present study was conducted to enhance the solubility and dissolution of a poorly aqueous soluble drug nevirapine via a pharmaceutical cocrystal.
P. Panzade, P. Somani, P. B. Rathi
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Pharmaceutical Cocrystal and Salts of Norfloxacin
Crystal Growth & Design, 2006The aim of this study was to investigate the structural and pharmaceutical properties of norfloxacin (a poorly soluble antibacterial drug), its cocrystal, and salts. Norfloxacin in the anhydrous form (form A, 1) was crystallized. It was cocrystallized with isonicotinamide (2), and organic salts were prepared with succinic acid, malonic acid, and maleic
Srinivas Basavoju +2 more
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Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy
X-ray diffraction is a commonly used technique in the pharmaceutical industry for the determination of the atomic and molecular structure of crystals.
Adam Sklenář +8 more
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X-ray diffraction is a commonly used technique in the pharmaceutical industry for the determination of the atomic and molecular structure of crystals.
Adam Sklenář +8 more
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Biochemical and Biophysical Research Communications - BBRC
A new cocrystalline form of metronidazole (MET) with propyl gallate (PRO), referred to as MET-PRO, has been successfully synthesized and characterized. Structural characterization reveals that MET and PRO are present in a 1:1 ratio within the cocrystal ...
Juan Chen +5 more
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A new cocrystalline form of metronidazole (MET) with propyl gallate (PRO), referred to as MET-PRO, has been successfully synthesized and characterized. Structural characterization reveals that MET and PRO are present in a 1:1 ratio within the cocrystal ...
Juan Chen +5 more
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Recent Patents on Drug Delivery & Formulation, 2019
AIM AND BACKGROUND The present study reports the formation of a cocrystal of candesartan with the coformer methyl paraben,its characterization and determination of its bioavailability.Candesartan is a poorly water soluble drug having an anti-hypertensive
Dipti Srivastava +4 more
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AIM AND BACKGROUND The present study reports the formation of a cocrystal of candesartan with the coformer methyl paraben,its characterization and determination of its bioavailability.Candesartan is a poorly water soluble drug having an anti-hypertensive
Dipti Srivastava +4 more
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Pharmaceutical cocrystals, salts and polymorphs: Advanced characterization techniques
Advanced Drug Delivery Reviews, 2017The main goal of a novel drug development is to obtain it with optimal physiochemical, pharmaceutical and biological properties. Pharmaceutical companies and scientists modify active pharmaceutical ingredients (APIs), which often are cocrystals, salts or carefully selected polymorphs, to improve the properties of a parent drug. To find the best form of
Edyta, Pindelska +2 more
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Solution Stability of Pharmaceutical Cocrystals
Crystal Growth & Design, 2022Amin Alvani, Ali Shayanfar
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