Results 121 to 130 of about 580,692 (357)

Concise Synthesis of Lacosamide with High Chiral Purity

ACS Omega, 2019
Meng-Di Chen, An-Jiang Yang, Zhong Li, Fei-Fei Hu, Jiang-Tao Yang, Sheng-Hua Gao, Fu-Li Zhang, Chun-Jie Zhao   +7 more
doaj   +1 more source

Design of a novel long-acting insulin analogs by acetylation modification and compared with insulin Icodec

Scientific Reports
Insulin is a potent medication for managing diabetes, yet its short half-life requires daily administration. Currently, Novo Nordisk’s icodec is the sole insulin available on the market that requires administration only once a week.
Min Yu, Chuanzhi Zhang, Hongjiang Xu, Yuanzhen Dong, Hongxiang Zhu, Chunguang Xia, Jun Feng   +6 more
doaj   +1 more source

The Potential Antinociceptive Effect and Mechanism of Cannabis sativa L. Extract on Paclitaxel-Induced Neuropathic Pain in Rats Uncovered by Multi-Omics Analysis

Molecules
Cannabis sativa L. (hemp) is a herbaceous plant rich in cannabinoids with a long history of use in pain treatment. The most well-characterized cannabinoids, cannabidiol (CBD) and Δ9-tetrahydrocannabinol (Δ9-THC), garnered much attention in chemotherapy ...
Yunhui Xu, Lijuan Yao, Yuhan Guo, Chenfeng Shi, Jing Zhou, Moli Hua   +5 more
doaj   +1 more source

Intellectual Capital Disclosure and Its Determinants: Empirical Evidence from Listed Pharmaceutical and Chemical Industry of Bangladesh

, 2019
Md. Musfiqur Rahman, Raihan Sobhan, Md. Shafiqul Islam   +2 more
openalex   +1 more source

TRIPS and the Pharmaceutical Industry in Bangladesh: Towards a National Strategy [PDF]

The paper presents a study of the WTO-Doha Declaration on TRIPS and Public Health and explores the opportunities of the growth of Bangladesh’s domestic pharmaceutical industry.
Professor Tony VanDuzer
core  

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

Innovation networks and competitive coalitionsin the pharmaceutical industry: The emergenceand structures of a new industrial organization [PDF]

, 2000
Marc‐Hubert Depret, Abdelillah Hamdouch   +1 more
openalex   +1 more source

Asymmetric Exchange Rate Exposure and Industry Characteristics : Evidence from Japanese Data [PDF]

This paper investigates the asymmetric effects of exchange rate exposure on Japanese stock returns at the industry level.Using the asymmetric correlation test of Hong et al.(2007), we examine five major currencies against the yen and thirty-three ...
Hsu, Chih-Chiang, Wu, Jyun-Yi, Yau, Ruey
core  

The Value of Failures in Pharmaceutical R&D [PDF]

, 2012
We build a cumulative innovation model in which both success and failure provide valuable information for future research. To test this learning mechanism, we use a dataset covering outcomes of world-wide R&D projects in the pharmaceutical industry, and ...
Chiou, Jing-Yuan, Magazzini, Laura, Pammolli, Fabio, Riccaboni, Massimo   +3 more
core  

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source