Results 121 to 130 of about 222,790 (315)

2D MOF with Intrinsic Porosity for Colorimetric Volatile Organic Compounds (VOCs) Detection

Advanced Materials, EarlyView.
An uncommon 2D MOF with intrinsic in‐plane porosity that can be mechanically exfoliated undergoes a distinct and reversible colour change upon exposure to various volatile organic compounds. ABSTRACT In this work, we report an uncommon 2D metal–organic framework (MOF) with intrinsic in‐plane porosity that undergoes a distinct and reversible colour ...
Sergio R. Gamarra, Alberto Fernández‐Alarcón, Joaquín Calbo, Enrique Ortí, Guillermo Mínguez Espallargas   +4 more
wiley   +1 more source

Enhancement of doxorubicin production in Streptomyces peucetius by genetic engineering and process optimization

AMB Express
Doxorubicin is an important class of anthracycline antitumor antibiotics produced by Streptomyces peucetius. The doxorubicin fermentation yield of the wild-type strain was very low, so it could not be produced directly by fermentation at an industrial ...
Songbai Yang, Jiali Gui, Zhengyu Zhang, Jiawei Tang, Shaoxin Chen   +4 more
doaj   +1 more source

Freeform Manufacturing of Plant‐Based Structural Colors for Scalable Photonic and Mechanochromic Devices

Advanced Materials, EarlyView.
A green, freeform manufacturing approach that utilizes robust aqueous two‐phase systems to create intricate and scalable photonic structures and non‐planar mechanochromic hydrogel actuators from plant‐based hydroxypropyl cellulose. This approach broadens the structural possibilities of sustainable photonic devices and mechanochromic systems, offering ...
Xiao Song, Peiqi Niu, Wenxi Gu, Chun Lam Clement Chan, Jiuhong Yi, Xu Liu, Peng Tan, Chon In Haydn Cheong, Qingwen Guan, Dan Fang, Bingpu Zhou, Zi Liang Wu, Ji Liu, Yan Yan Shery Huang, Iek Man Lei   +14 more
wiley   +1 more source

Patents and pharmaceutical drugs : understanding the pressures on developing countries [PDF]

This paper offers a discussion to the question of why there are pressures on developing countries for introducing and/or reinforcing patent protection to pharmaceutical drugs. Patent protection is an important component of a complex strategy developed by
Nogues, Julio
core  

Actuation of Cell Layers in Three Dimensions

Advanced Materials, EarlyView.
ABSTRACT The alignment of fibers and cells in living tissues affect their mechanical properties and functionality. In this context, one can draw an analogy between tissues and nematic liquid crystal elastomers. We explore this analogy by growing fibroblasts on 2D‐patterned substrates and observing the contraction of cell sheets upon detachment from the
Kirsten Endresen, Aniruddh Murali, Birte C. Geerds, Grecia M. Valenzuela Portillo, Maria Bloksgaard, Daniel J.G. Pearce, Francesca Serra   +6 more
wiley   +1 more source

The Potential Antinociceptive Effect and Mechanism of Cannabis sativa L. Extract on Paclitaxel-Induced Neuropathic Pain in Rats Uncovered by Multi-Omics Analysis

Molecules
Cannabis sativa L. (hemp) is a herbaceous plant rich in cannabinoids with a long history of use in pain treatment. The most well-characterized cannabinoids, cannabidiol (CBD) and Δ9-tetrahydrocannabinol (Δ9-THC), garnered much attention in chemotherapy ...
Yunhui Xu, Lijuan Yao, Yuhan Guo, Chenfeng Shi, Jing Zhou, Moli Hua   +5 more
doaj   +1 more source

R&D Portfolios and Pharmaceutical Licensing [PDF]

We examine how R&D portfolios of drug pipelines affect pharmaceutical licensing, controlling firm size, diversity, and competitors in R&D and product markets.
Junichi Nishimura, Yosuke Okada
core  

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Recent Progress in the Phase‐Controlled Synthesis of Ruthenium Nanocrystals for Catalytic Applications

Advanced Materials, EarlyView.
Template effect and kinetic control enable crystal‐phase engineering of Ru nanocrystals, granting access to either metastable fcc‐Ru or stable hcp‐Ru with distinct surface structures, thermal stabilities, and catalytic behaviors. Moreover, the hcp‐Ru can further serve as an epitaxial template to direct Pd and Rh nanocrystals into the metastable hcp ...
Jianlong He, Zhiqi Wang, Jiaqi Guan, Younan Xia   +3 more
wiley   +1 more source

Design of a novel long-acting insulin analogs by acetylation modification and compared with insulin Icodec

Scientific Reports
Insulin is a potent medication for managing diabetes, yet its short half-life requires daily administration. Currently, Novo Nordisk’s icodec is the sole insulin available on the market that requires administration only once a week.
Min Yu, Chuanzhi Zhang, Hongjiang Xu, Yuanzhen Dong, Hongxiang Zhu, Chunguang Xia, Jun Feng   +6 more
doaj   +1 more source