Results 121 to 130 of about 3,606,854 (303)

Longitudinal Study on the Performance of U.S. Pharmaceutical Firms: The Increasing Role of Marketing [PDF]

open access: yes
Nowadays, the U.S. pharmaceutical industry has been under thorough scrutiny. Popular press claims of intensive marketing activities that go beyond R&D, the strong increase of me-too drugs, and, at the same time, the high industry profitability have ...
Pattikawa, L.H.
core  

Biointegrated Battery‐Based Electroceuticals

open access: yesAdvanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou   +6 more
wiley   +1 more source

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

open access: yesAdvanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà   +15 more
wiley   +1 more source

Research Progress on Conformational Polymorphism of Flexible Chain Molecules: Solid-State Structures, Regulation Strategies, and Functional Correlations

open access: yesPharmaceutical Fronts
This review aims to elucidate the mechanisms underlying conformational changes of drug molecules during crystallization and to investigate how these changes affect the physicochemical properties and biological characteristics of pharmaceuticals.
Gang Li   +7 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Enhancement of doxorubicin production in Streptomyces peucetius by genetic engineering and process optimization

open access: yesAMB Express
Doxorubicin is an important class of anthracycline antitumor antibiotics produced by Streptomyces peucetius. The doxorubicin fermentation yield of the wild-type strain was very low, so it could not be produced directly by fermentation at an industrial ...
Songbai Yang   +4 more
doaj   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

open access: yesAdvanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian   +7 more
wiley   +1 more source

Sustainable Plant‐Based Water Repellent Coatings Using Hydrophobic Pine and Palm Pollen

open access: yesAdvanced Materials Interfaces, EarlyView.
A novel formulation strategy for creating superhydrophobic coatings using plant‐derived waxes and chemically treated pine and palm pollen. By employing acid modification, the hydrophobicity of the pollen surface is enhanced, resulting in water contact angles exceeding 150°.
Brenda Resendiz‐Diaz   +2 more
wiley   +1 more source

Overcoming Innovation Limits through Outward FDI: The Overseas Acquisition Strategy of Indian Pharmaceutical Firms [PDF]

open access: yes
A host of strategic government policies including a process patent regime led to the rise of Indian pharmaceutical firms with significant process development capabilities.
Pradhan, Jaya Prakash
core  

Imide Substitution Drives the Supramolecular Assembly of Perylene Diimide Into Laterally Modulated Metallic/Semiconducting Molecular Patterns

open access: yesAdvanced Materials Interfaces, EarlyView.
Imide substitution with bulky 2,6‐isopropylphenyl groups induces perylene diimide to self‐assemble on Ag(111) into a monolayer with two coexisting adsorption heights. Molecules closer to the substrate gain metallic character due to charge transfer from the metal, while farther ones remain decoupled and semiconducting.
Giacomo Agnesod   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy