Results 141 to 150 of about 4,006,128 (388)

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

The Potential Antinociceptive Effect and Mechanism of Cannabis sativa L. Extract on Paclitaxel-Induced Neuropathic Pain in Rats Uncovered by Multi-Omics Analysis

Molecules
Cannabis sativa L. (hemp) is a herbaceous plant rich in cannabinoids with a long history of use in pain treatment. The most well-characterized cannabinoids, cannabidiol (CBD) and Δ9-tetrahydrocannabinol (Δ9-THC), garnered much attention in chemotherapy ...
Yunhui Xu, Lijuan Yao, Yuhan Guo, Chenfeng Shi, Jing Zhou, Moli Hua   +5 more
doaj   +1 more source

Policy-makers in the Pharmaceutical Industry [PDF]

, 1965
S. Bradshaw
openalex   +1 more source

Early Academis Science and the Birth of Industrial Research Laboratories in the U.S. Pharmaceutical Industry [PDF]

The establishment and growth of industrial research laboratories is one of the key organizational innovations affecting technological progress in the United States in the 20th century.
Jeffrey L. Furman, Megan MacGarvie
core  

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Design of a novel long-acting insulin analogs by acetylation modification and compared with insulin Icodec

Scientific Reports
Insulin is a potent medication for managing diabetes, yet its short half-life requires daily administration. Currently, Novo Nordisk’s icodec is the sole insulin available on the market that requires administration only once a week.
Min Yu, Chuanzhi Zhang, Hongjiang Xu, Yuanzhen Dong, Hongxiang Zhu, Chunguang Xia, Jun Feng   +6 more
doaj   +1 more source

Health and Safety in the Pharmaceutical Industry [PDF]

, 1964
Allan P. Skoog
openalex   +1 more source

Law Enforcement as Legal Mobilization: Reforming the Pharmaceutical Industry Through Government Litigation [PDF]

, 2015
Scholars of legal mobilization have long explored how litigation is used as a resource for social and political change. While most studies focus on the actions of private groups, this article considers law enforcement as a form of legal mobilization ...
Nolette, Paul
core   +1 more source

Copper‐based Materials for Photo and Electrocatalytic Process: Advancing Renewable Energy and Environmental Applications

Advanced Functional Materials, EarlyView.
Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida, Yanjie Wang, Thais A. Rodrigues, Paulo H. H. Nunes, Vagner R. de Mendonça, Paulo H. E. Falsetti, Leticia V. Savazi, Tao He, Alexandra V. Bardakova, Aida V. Rudakova, Jie Tian, Alexei V. Emeline, Osmando F. Lopes, Antonio Otavio T. Patrocínio, Jia Hong Pan, Caue Ribeiro, Detlef W. Bahnemann   +16 more
wiley   +1 more source

Book Review: A Healthy Business. World Health and the Pharmaceutical Industry [PDF]

, 1991
Anthony Barker
openalex   +3 more sources