Results 111 to 120 of about 258,478 (322)
Регуляторные исследования и экспертиза лекарственных средствToday, the pharmaceutical industry is on the cusp of a “digital renaissance”, where artificial intelligence (AI) and science complement each other. The use of bioinformatics, machine learning, and AI unlocks new opportunities for optimising all stages of
L. I. Shcherbakova, P. P. Rodionov
doaj +1 more source
Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
Advanced Functional Materials, EarlyView.CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham +9 more
wiley +1 more source
Leading pharmaceutical and chemical companies have their NEW ORGANIC CHEMICALS manufactured by Trubek [PDF]
, 1963 openalex +1 more source
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
Advanced Functional Materials, EarlyView.This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer +10 more
wiley +1 more source
GAF custom manufacture of pharmaceutical and agricultural chemicals. We make them accurately and economically for you...because that's how we do it for ourselves. [PDF]
, 1979 openalex +1 more source
Advanced Functional Materials, EarlyView.A self‐sustaining solar photoelectrochemical cell (SS‐PEC) is developed to recover uranium from aqueous UO22+ with concurrent organic oxidation and electricity production. The monolithical photoanode directly captures electrons from organic compounds, leading to the oxidation of organic compounds and the decomposition of uranium‐organic complexes ...
Yumei Wang +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A metal halide perovskite‐based photoanode integrated with a CoNiFe layered double hydroxide (LDH) cocatalyst is reported for selective glucose oxidation reaction (GOR), achieving simultaneous and unassisted photoelectrochemical hydrogen production. This system delivers high photocurrent density, excellent Faradaic efficiency of GOR, and strong techno ...
Shujie Zhou +12 more
wiley +1 more source