Results 141 to 150 of about 258,478 (322)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Die Produktion von Wirkstoffen bei Roche; gestern, heute, morgen

CHIMIA, 1996
During Roche's first 100 years, production of pharmaceutical active ingredients was a key component in the company's business. This article traces changes in manufacturing technology and methods and looks at the demands placed on pharmaceutical ...
Benno Jermann, Stefan Müller
doaj   +2 more sources

Current and future prospective of pharmaceutical manufacturing in Saudi Arabia. [PDF]

Saudi Pharm J, 2023
Alshehri S, Alshammari R, Alyamani M, Dabbagh R, Almalki B, Aldosari O, Alsowayigh R, Alkudeer A, Aldosari F, Sabr J, Shakeel F.   +10 more
europepmc   +1 more source

Composites of Shellac and Silver Nanowires as Flexible, Biobased, and Corrosion‐Resistant Transparent Conductive Electrodes

Advanced Functional Materials, EarlyView.
Shellac, a centuries‐old natural resin, is reimagined as a green material for flexible electronics. When combined with silver nanowires, shellac films deliver transparency, conductivity, and stability against humidity. These results position shellac as a sustainable alternative to synthetic polymers for transparent conductors in next‐generation ...
Rahaf Nafez Hussein, Tiago Carneiro Gomes, Eliza Ng, Simon Rondeau‐Gagné, Tricia Breen Carmichael   +4 more
wiley   +1 more source

Tailored Reconstruction of Polycrystalline CuO Nanorods Promotes C─C Coupling in CO2 Electroreduction

Advanced Functional Materials, EarlyView.
Controlling the polycrystallinity of CuO nanorods enables directional reconstruction into rod‐like structures that stabilize Cu(OH)2 and increase Cu+ ratios, while modulating interfacial water dynamics to enhance C─C coupling and boost C2+ product formation in CO2 electroreduction.
Hyeon‐Seok Bang, Young‐Jin Ko, Hyo Sang Jeon, Eugene Huh, Eung Dab Kim, Min Gwan Ha, Chulwan Lim, Jiho Jeon, Seohyeon Ka, Dogyeong Kim, Xiaojie Zhang, Yeongjin Kim, Kyeongsu Kim, Woong Hee Lee, Jae‐Young Choi, Hyung‐Suk Oh   +15 more
wiley   +1 more source

Empowering Africa's healthcare future: The crucial role of human capital development in bio- and pharmaceutical manufacturing. [PDF]

J Public Health Afr, 2023
Mynhardt M, Mwila C, Habtemariam MK, Tshangela A, Martinez M, Ngongo N, Kaseya J, Ndembi N.   +7 more
europepmc   +1 more source

Training of pharmacists in Zambia: developments, curriculum structure and future perspectives [PDF]

, 2019
In Zambia, local training of pharmacists commenced in 2001. Development of pharmaceutical education in Zambia has been largely influenced by the national need for pharmacists in the healthcare sector. Training institutions offer the Bachelor of Pharmacy (
Apampa, Bugewa, Chichonyi Kalungia, Aubrey, Marshall, Sarah, May, Claire, Munkombwe, Derick, Tyson Muungo, Lungwani   +5 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Evidence of Reliable Gastro-Resistance of Novel Enteric Ready-to-Fill Capsules Simplifying Pharmaceutical Manufacturing. [PDF]

Pharmaceutics, 2023
Afonso Urich JA, Fedorko A, Hölzer B, Khinast J.   +3 more
europepmc   +1 more source

Mixing of pharmaceutical powders and granules. I. Effect of grain size on the manufacturing process.

, 1982
Hiroshi Fujiwara, Susumu Kawashima, Sachiko Omura   +2 more
openalex   +2 more sources