Results 151 to 160 of about 2,517,866 (353)

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Nitrite in Pharmaceutical Manufacturing Water: Development of an Ultra-Sensitive Analytical Method, Typical Data, and Discussion of Potential Nitrosamine Formation in Drug Substance and Drug Product from Water [PDF]

A. B. Suresh Kumar, Debasis Dey, T. S. Balaji, Haridoss Karthik, K. Sathishkumar, Paul McDaid, Brian Fitzpatrick, Atul Awasthi, Simon Davies, Olivier Dirat   +9 more
openalex   +1 more source

Predictive Machine Learning Models for Calibration Failure Detection in Pharmaceutical Manufacturing

, 2022
Srikanth Reddy Katta
openalex   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

Advanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird, Connor Smith, Nahal Habibi, Samantha Rivera, Saeed Mortezazadeh, Reece Martin, Benjamin M. Geilich, Gilles Besin, Borries Demeler   +8 more
wiley   +1 more source

Pharmaceutical Manufacturing Plan for Africa is critical for pandemic preparedness, prevention and response. [PDF]

J Public Health Afr, 2023
Mynhardt M, Ndembi N.
europepmc   +1 more source

Operational Excellence: A Model Pathway to Improve Yield and Productivity of the Pharmaceutical Tablet Manufacturing Process [PDF]

Devyani Pravin Chavan, Mrs.Vishakha D. Chavan, Pratiksha Narayan Sonwane, Priya Manik Gadakh, Sarika Vinayak Patil, Suchita Shirsath   +5 more
openalex   +1 more source

Technological Inputs and Productivity Growth in China�s High-Tech Industries [PDF]

high-tech, China, growth ...
Szirmai, A.S., Wang, L.
core  

Proteins, Processing, and Properties of Adhesive Fluid Condensates Purified from Mussels

Advanced Functional Materials, EarlyView.
Mussels exhibit an unmatched proficiency for adhering to wet surfaces in salty environments—a remarkable ability that could inspire new biomedical and technical glues. The fluid protein condensates used to form the underwater mussel glue are extracted, reconstituted and characterized with advanced spectroscopy and nanomechanical analysis, revealing ...
Mathieu D. Rivard, Max Renner‐Rao, Nahid Hassanpour, Franziska Jehle, Chang‐Sheng Wang, Duy Anh Pham, Daniel J. Jackson, Xavier Banquy, Matthew J. Harrington   +8 more
wiley   +1 more source

Making Do in Making Drugs: Innovation Policy and Pharmaceutical Manufacturing

, 2013
W. Nicholson Price
openalex   +1 more source