Cold Quad‐Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking
Multimodal albumin–bismuth sulfide–superparamagnetic iron oxide (ABS) nanocomplexes are developed for stem cell tracking across four different imaging modalities: MRI, MPI, MSOT, and CT. Combining its flexibility with high sensitivity, this quad‐modal imaging agent enables a robust quantification of ABS‐labeled stem cells in vivo.
Ali Shakeri‐Zadeh +4 more
wiley +1 more source
Die Produktion von Wirkstoffen bei Roche; gestern, heute, morgen
During Roche's first 100 years, production of pharmaceutical active ingredients was a key component in the company's business. This article traces changes in manufacturing technology and methods and looks at the demands placed on pharmaceutical ...
Benno Jermann, Stefan Müller
doaj +2 more sources
Pullulan, a biomass‐derived polysaccharide, is transformed into transparent optical fibers using a solvent‐free borax hydrogel‐spinning method. The fibers outperform PMMA with ≈200 MPa tensile strength and 200 °C stability, while uniquely guiding visible‐to‐NIR light and enabling additive‐free humidity sensing.
Yuya Fukata +4 more
wiley +1 more source
Manufacturing capability as a technological development indicator in the pharmaceutical industry
The pharmaceutical industrial has five subsectors: medicines, cosmetics, phytotherapeutics, cleaning products and medical devices. The medicine subsector consists of organisations producing, importing and selling these products.
John Jairo Gallo Castro +2 more
doaj
Using PharmaPy with Jupyter Notebook to teach digital design in pharmaceutical manufacturing. [PDF]
Laky DJ +6 more
europepmc +1 more source
Hybrid Rule-based and Optimization-driven Decision Framework for the Rapid Synthesis of End-to-End Optimal (E2EO) and Sustainable Pharmaceutical Manufacturing Flowsheets [PDF]
Yash Barhate +4 more
openalex +1 more source
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy +3 more
wiley +1 more source
Current and future prospective of pharmaceutical manufacturing in Saudi Arabia. [PDF]
Alshehri S +10 more
europepmc +1 more source
Reply to Miller et al. Comment on “Hermeling et al. Nano-Dry-Melting: A Novel Technology for Manufacturing of Pharmaceutical Amorphous Solid Dispersions. Pharmaceutics 2022, 14, 2145” [PDF]
Malin Hermeling +4 more
openalex +1 more source
Theory‐Guided Design of Non‐Precious Single‐Atom Catalyst for Electrocatalytic Chlorine Evolution
To overcome the reliance on noble metals for the chlorine evolution reaction (CER), we designed a non‐precious single‐atom catalyst (SAC), NiN3O–O. It achieves a low overpotential of 75 mV, 95.8% Cl2 selectivity, and outperforms commercial dimensionally stable anodes (DSAs).
Kai Ma +9 more
wiley +1 more source

