AI-integrated IQPD framework of quality prediction and diagnostics in small-sample multi-unit pharmaceutical manufacturing: Advancing from experience-driven to data-driven manufacturing. [PDF]
Acta Pharm Sin BWang K +13 more
europepmc +1 more source
Advanced Materials Technologies, EarlyView.This study presents a novel platform for assessing the active mechanical behavior of living cardiac microbundles through localized nanoindentation, integrated with temperature regulation and dual‐camera imaging systems. The developed system enables quantitative evaluation of dynamic micromechanics in engineered cardiac tissues in vitro, offering ...
Lihua Lou +4 more
wiley +1 more source
Erratum: Author correction to "AI-integrated IQPD framework of quality prediction and diagnostics in small-sample multi-unit pharmaceutical manufacturing: advancing from experience-driven to data-driven manufacturing" [Acta Pharm Sin B 15 (2025) 4193-4209]. [PDF]
Acta Pharm Sin BWang K +13 more
europepmc +1 more source
Advanced Materials Technologies, EarlyView.A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey +6 more
wiley +1 more source
BLOC: Buildable and Linkable Organ on a Chip
Advanced Materials Technologies, EarlyView.We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura +7 more
wiley +1 more source
Vat Polymerization 3D Printing for Controlled Drug Release Applications
Advanced Materials Technologies, EarlyView.ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari +2 more
wiley +1 more source
Compliance of Pharmaceutical Manufacturing Companies to Good Manufacturing Practices in Heating, Ventilation, and Air-Conditioning Systems: The Case of Local Ethiopian Firms. [PDF]
Adv Pharmacol Pharm SciTune Tibesso D +3 more
europepmc +1 more source
Advanced Materials Technologies, EarlyView.This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li +7 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source
Evaluation of Prediction Models for the Capping and Breaking Force of Tablets Using Machine Learning Tools in Wet Granulation Commercial-Scale Pharmaceutical Manufacturing. [PDF]
Pharmaceuticals (Basel)Kim SH, Han SH, Seo DW, Kang MJ.
europepmc +1 more source