Results 101 to 110 of about 3,602,513 (298)

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source

FEATURES OF THE INNOVATION PROCESS AT THE UKRAINIAN PHARMACEUTICAL ENTERPRISES

Вісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2013
The paper deals with key theories of innovative process organization. Basic features of main stages of the innovative process on the pharmaceutical market of Ukraine are determined.
O. Chulak
doaj   +1 more source

New Approved Drugs Appearing in the Pharmaceutical Market in 2022 Featuring Fragments of Tailor-Made Amino Acids and Fluorine. [PDF]

Molecules, 2023
Wang N, Mei H, Dhawan G, Zhang W, Han J, Soloshonok VA.   +5 more
europepmc   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

The modern Russian pharmaceutical market: consumer attitudes towards distance retailing of medicines. [PDF]

BMC Health Serv Res, 2022
Lobuteva L, Lobuteva A, Zakharova O, Kartashova O, Kocheva N.   +4 more
europepmc   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

THE INTERNATIONAL PRACTICE OF DRUG SUPPLY IN THE OUTPATIENT SEGMENT

Фармакоэкономика, 2018
The paper examines the international experience of drug supply and the risks faced by countries using various systems of drug provision to the population in the outpatient settings. The option of introducing a system of drug supply or drug insurance with
D. V. Lukyantseva, L. S. Mel’nikova, A. P. Tatarinov   +2 more
doaj   +1 more source

The Impact of Reimbursement Practices on the Pharmaceutical Market for Off-Patent Medicines in Slovakia. [PDF]

Front Pharmacol, 2021
Tesar T, Golias P, Masarykova L, Kawalec P, Inotai A.   +4 more
europepmc   +1 more source

Triplet Energy Transfer‐Driven Intermolecular [2+2] Photocycloaddition of Acyclic Imines and Indoles: Facile Access to Azetidine‐Fused Indolines

Advanced Science, EarlyView.
An intermolecular aza‐Paternò‐Büchi reaction of indoles and acyclic imines is enabled by visible‐light‐driven triplet energy transfer, providing azetidine‐fused indolines up to 93% yield for 30 examples and providing a novel protocol to access previously inaccessible scaffolds. ABSTRACT Currently, successful examples of the aza‐[2+2] photocycloaddition
Gang Yang, Zeng Han, Hong Zhang, Xiuling Cui   +3 more
wiley   +1 more source

Socio-economic significance and characteristic features of pharmacy [PDF]

Problemi Ekonomiki, 2013
The article considers main factors indicative of significance of the world pharmaceutical industry in the global economy. It shows the total volume of the world pharmaceutical market and regional structure of the world pharmaceutical production. It marks
Tischenko Aleksandr N., Dorovsky Oleksandr V.   +1 more
doaj